The Related Research Of Phlegm Physical And The Characteristics Of Endocrine And Metabolic With Polycystic Ovary Syndrome (PCOS)

Objective: This study which comparative analyzes Physique phlegm and non-physicalphlegm in patients of PCOS with the characteristics of endocrine and metabolism, provide apersonalized basis for the diagnosis and treatment of PCOS, improving the recent therapeuticeffect of PCOS and preventing the long-term complications.Methods: according to the Physique criteria formulated by the Chinese MedicalAssociation,divide88patients with polycystic ovary syndrome who meet the inclusioncriteria into physical phlegm group and non physical phlegm group. Record the treatmentcard number, name, phone, home address, age, occupation, menstrual history, obstetricalhistory and family history, height, weight, and calculate the body mass index (BMI) of thepatients. All patients in the3-5th day of the menstrual cycle，or the3-5th day of theprogesterone withdrawal blood, or the amenorrheas whose endometrial≤5mm, pump thefasting venous blood in the morning，to test the six hormones, the glucose tolerance（OGTT）（four times) and the insulin release（IRT）（four times), and calculate the ratio of luteinizinghormone/follicle stimulating hormone (LH/FSH) and the insulin resistance index(HOMA-IR). Collect the data and the information for statistical analysis.Results:①The distribution of physical:37patients with physical phlegm, accounting for42.05%,51patients with non-physical phlegm(Yin deficiency, gentleness, blood stasis,damp-heat, yang quality, qi quality, qi deficiency, especially intrinsic quality), accountingfor57.95%;②The distribution of Obesity:37patients with obesity in the physical phlegmgroup, the occurrence rate is51.35%,12patients with obesity in the non-physical phlegmgroup, accounting for23.53%, the difference is statistically significant (P <0.05);③The hormone levels of the two groups:The levelsof LHand Tin the Phlegmhysical groupishigherthan that in the non-Phlegm physical group, and the difference is statistically significant (P <0.05);5patients with LH/FSH>2.0in the physical phlegm group, accountingfor13.51%, but22patients with LH/FSH>2.0in the non-physical phlegm group, accountingfor43.14%, the difference is statistically significant (P <0.05);10patients with T>0.75ng/ml in the physical phlegm group, accounting for27.03%, but17patients with T>0.75ng/ml in the non-physical phlegm group, accounting for33.33%, the difference is nostatistically significant (P>0.05);④The distribution of IR:17patients with IR in the physicalphlegm group, the occurrence rate is45.95%,6patients with IR in the non-physical phlegmgroup, accounting for11.76%, the difference is statistically significant (P <0.05);⑤Thedistribution of OGTT abnormalities:22patients with abnormal OGTT in the physicalphlegm group, the occurrence rate is59.46%,12patients with abnormal OGTT in thenon-physical phlegm group, accounting for23.53%, the difference is statistically significant(P <0.05);⑥65patients with the non-IR in the the two groups, of which18patients areabnormal OGTT, accounting for27.69%;⑦The FPG, the FINS, the BMI and the HOMA-IRof the phlegm physical group are all higher than those of the phlegm physical group, thedifferences are all statistically significant (P <0.05);⑧The BMI and the HOMA-IR arepositive correlation in the patients in both the physical phlegm group and the non-physicalphlegm group with PCOS;⑨The FPG, the FINS, the blood glucose after oral surger60minutes、120minutes、180minutes, and the insulin after oral surger60minutes、120minutes、180minutes and the HOMA-IR of the two groups are straight relationship, and is apositive correlation.Conclusion:①physical phlegm is a predisposition of PCOS;②The patients with PCOS inthe physical phlegm group prone to obesity, insulin resistance and impaired glucosetolerance; some patients with PCOS in the non-physical phlegm group also existobesity,insulin resistance and impaired glucose tolerance;③27.69%of the PCOS patientsin the non-IR group have abnormal OGTT;④The patients with PCOS are prone to haveHA, but the patients with PCOS in the non-physical phlegm group are more likely to havehigh LH of phlegm hyperlipidemia.