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The Constitution Of Traditional Chinese Medicine And PMOP Correlation Research

Posted on:2015-01-24Degree:MasterType:Thesis
Country:ChinaCandidate:Q H WangFull Text:PDF
GTID:2284330431482129Subject:Internal medicine of traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
Objective: Through the questionnaire in patients with postmenopausalosteoporosis, trying to find out the main body type, and early intervention, and toprovide new ideas for the research on the causes of PMOP, provide a new referencefor the prevention and treatment.Methods:(1) preparation of postmenopausal osteoporosis related factorsquestionnaire, and then make a preliminary investigation. Preliminary survey,questionnaire reliability and validity of the evaluation, USES the analysis crownsBach coefficient of the reliability and structural validity, heavy test method.(2)clinical investigation: the first affiliated hospital in henan college of traditionalChinese medicine hospital based case-control method research, using the samequestionnaire (traditional Chinese medicine health scale, PMOP related factorsquestionnaire) on the investigation of the control group (287cases) and group (273cases) of cases to investigate, collect data obtained from survey data, and then USESthe logistic regression analysis data, to explore the constitution types associated withfemale PMOP. Finally, the proposed women PMOP from the perspective of TCMconstitution of tertiary prevention strategies.Results:(1) through the questionnaire reliability and validity of the analysis ofthe questionnaire were modified and adjusted entries.(2) general information: the ageof the case group and control group the difference after inspection without statisticalsignificance (P>0.05), comparable.2a group of body mass index, bone masscompared data distribution characteristics were all statistically significant (P <0.05);Case group and control group subjects in national, place of residence, culture degree,size composition than comparison, all P values <0.05, all differences have statisticalsignificance.(3) related factors: sunshine time constitute each day is better than thetwo groups, comparing the status of the height to reduce the difference had statisticalsignificance (P <0.05); Comparison situation, menstruation menarche age differencehas no statistical significance (P>0.05), age of menopause and despair of comparison, difference was statistically significant (P value is0.000).(4) PMOP constitution typesof single factor the unconditioned logistic regression analysis results show that theYang deficiency constitution, Yin deficiency, blood stasis constitution health, peaceconstitution respectively corresponding to the P values were less than0.05,(OR=2.223) of Yang deficiency constitution, Yin deficiency constitution OR a value of1.968,(OR=2.568) of blood stasis constitution, peace constitution OR value is equalto0.326, henan PMOP TCM constitution type of multi-factor regression equations forunconditional logistic regression analysis: Logit (P)=ln (1-P/P)=0.218+0.799X1+0.677X2(Yang deficiency constitution)(Yin deficiency constitution)+0.943X6(blood stasis constitution)-1.120X9(peace constitution); Yang deficiencyconstitution model of fitting unconditioned logical stepwise regression results: size (P=0.003), salt (P=0.018), sports (P=0.002), disease (P=0.023), age of menopause (P=0.007) in the end into the regression model, salt (OR=3.385),(OR a value of1.935)disease, menopause age (OR=1.292) and the occurrence of Yang deficiencyconstitution, is a risk factor, shape (OR=0.152), sports (OR=0.225) and negativelyrelated to the performance of Yang deficiency constitution, is the protective factors;Yin deficiency constitution model fitting unconditioned logistic regression resultsshows: in the end into the main effect model, the influence factors of variable values(P=0.009) for a drink, food collocation situation (P=0.006) and body mass index (P=0.000), drinking (OR=3.690), dietary collocation situation (OR=2.869) and theperformance is positively related to the formation of Yin deficiency constitution, thebody mass index (OR=0.789) and Yin deficiency constitution show the negativecorrelation; Blood stasis constitution model fitting unconditioned logistic regressionanalysis results: the results have significant variables for smoking situation (P=0.004), disease (P=0.005), the number of fertility (P=0.007), smoking (OR=4.032),the disease situation (OR=2.963), the number of birth (OR=4.506) is and a riskfactor for the occurrence of blood stasis constitution were positively correlated. Peaceconstitution model fitting unconditioned logical stepwise regression results: in the endinto the model of the related factors of culture (P value is0.004), sports (P=0.013),calcium (P value is0.012), calcium (OR=2.405), education (OR value is5.272),sports (OR=6.861) peace and physical performance is positively related to happenOR not, degree of culture is the technical secondary school OR above people thanpeople under primary school more greater peace qualitative (OR value is equal to5.272), and people often exercise than people who do not exercise form would have a greater chance and qualitative (OR value is6.861).Conclusions:1.The constitution as the starting point to establish thepredisposition of postmenopausal osteoporosis with Yin deficiency constitution, Yangdeficiency constitution, blood stasis constitution, protective constitution is peaceconstitution, make the onset of PMOP theory more rich.Predisposition is the greatestinfluence in the blood stasis, followed by Yang deficiency.2. By exploring the connection between the constitution types and factorsaffecting PMOP, preliminary get there are five, and Yang qualitative factors associatedwith diseases, salt, despair age are risk factors, protection factor is the movement andbody; Associated with Yin deficiency constitution factors including alcoholconsumption, body mass index and dietary collocation, drinking, diet collocation(mainly non-vegetarian meals) is it easy to form the danger of Yin deficiencyconstitution factors, body mass index is the formation of the protective factors; Andthe formation of blood stasis constitution expression is positively related to thenumber of factors including birth situation, chronic diseases, smoking; Three factorspeace culture, calcium supplements, sports and mass are related.3.Tentative designs of PMOP with TCM constitution type as the starting point ofthe tertiary prevention strategies.
Keywords/Search Tags:Postmenopausal osteoporosis, Constitution, Correlationanalysis, Clinical epidemiology
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