Thoracoscopic Resection Clinical Analysis Of Survival And Prognostic Factors Of Non-small Cell Lung Cancer

Objective:The main is based on the previous research results and existingproblems, and extensively collected Third class A hospitals in thelocality,between January2008and February2013cases under thoracoscoperesection of non-small cell lung cancer disease1328cases, adopt the c-VATSand a-VATS two kinds of technology to complete, comprehensive analysis ofvarious factors may affect the prognosis of non-small cell lung cancer, theobjective evaluation of the influence of various factors on the survival time,summed up the impact non-small cell lung cancer survival time independentprognostic factors, so as to provide a certain basis for this kind of patientcare.given the large number of prognosis of non-small cell lung cancer resectionunder thoracoscope related research, and made some achievements, it isconcluded that the prognosis of non-small cell lung cancer is mainly related tothree factors: individual factors, tumor factors, treatment.But as a result ofvarious reported cases and research methods, three aspects factors contained inthe results can’t be consistent, and research for retrospective data analysis!Smallsample sizes, hierarchical analysis is difficult to achieve.Therefore, the purposeof this paper is to through a lot of samples, correlation analysis to conduct acomprehensive study is necessary to further expand, lung cancer prognosis model is set up to provide individualized treatment plan to provide importantbasis for clinical.Methods:Third class A hospitals in the locality, from January2008toFebruary2013, the c-VATS and a-VATS of two kinds of technology tocomplete the cases under thoracoscope resection of non-small cell lung cancerdisease,1328cases of patients as the research object.To non-small cell lungresection under thoracoscope patients in the form of questionnaires toinvestigate.The questionnaire with the method of randomdistribution.Questionnaire was designed to investigate the condition ofpostoperative patients, quality of life and the regularity of family history, lifeand so on.Ask experts to ensure the quality of questionnaire design to the designof questionnaire, content, validity of inspection and measurement of thequestionnaire, and then modify, supplement, finally determined to be the formalquestionnaire.Reliability testing of the questionnaire adopts the "test method",namely: within60days after issue the same object with the same questionnaire,correlation coefficient, to determine the questionnaire reliability.All the researchdata is using SPSS16.0statistical software system for processing, test data areused (mean and standard deviation), each pairing comparison before and afterthe experiment USES the T test, comparison between groups using independentsample t-test analysis, significant level at p <0.05.Results:Patients in the preoperative staging,550people Ⅰperiod (41.4%),367people Ⅱp eriod (27.6%),390people Ⅱp eriod (29.4%),21Ⅱperiod(1.6%).66needy patients transformation of the mode of operation (c-VATS turnto a-VATS, n=60; by c-VATS transferred to open surgery, n=2; by a-VATStransferred to open surgery, n=4).Kaplan-meier curve shows that: the mediansurvival for patients with Ⅰperiod is45months, the median survival for patients with Ⅱp eriod is39months, the median survival for patients with Ⅱperiod is35months, the median survival for patients with Ⅱperiod is10months, thedifference statistically significant (p <0.05).Median survival for patients withPT2cm or less is59months,2<median survival for patients with PT3cm orless is42months,<3PT5cm or less patients with median survival was32months,5<median survival for patients with PT7cm or less is16months, PT> median survival for patients with7cm is6months;Tumor size has asignificant effect on the median survival, statistically significant difference (P <0.05).Female patients with a median survival of47months, male patients withmedian survival was29months, the median survival period there weresignificant differences between genders, statistically significant (P <0.05).Pneumonectomy patients with median survival was17months, the mediansurvival of pneumonectomy patients for46months, surgical removal of the waya median survival of patients with significant effect, statistically significantdifference (p <0.05).No patients died in the surgery,24people (0.2%) died afteroperation.The total incidence was8.7%.Through the Log-rank test and Breslowtest analysis, clear tumor stage, tumor size, surgical removal of the way andgender on the median survival in patients with impact is bigger, have significantdifference (p <0.05).Conclusion:video-assisted thoracoscope assisted or under video-assistedthoracoscope surgery treatment of lung cancer patients with resectablealternative to traditional thoracotomy lung cancer surgery.Thoracoscope surgeryin perioperative period has obvious advantages of minimally invasive andobvious long-term curative effect, believe in the near future there will be moreand more medical institutions use the technology to treat lung cancer.Statisticalmultivariate analysis method is also proved that the tumor of the lung cancer patients, TMN clinical stage, surgical removal of the way (that is, the tumorfactors, individual factors and treatment) is to determine the decisive factors inlong term survival in patients with lung cancer.