The Clinical Retrospective Analysis Of110Cases Acute Myelopathy In Childhood

Objective： To understand the clinical manifestation, laboratoryexamination, treatment and prognosis of the acute myelopathy caused bydifferent etiology in children, with special emphasis on the diagnosis anddifferential diagnosis to improve early diagnosis and judge the prognosis．Method: A retrospective study of110acute myelopathy patientshospitalized from January2004to December2013was performed inChongqing Medical University affiliated children’s hospital. Thisretrospective study was carried out according to medical history of patients,clinical manifestation, auxiliary examinations, treatment processes andfollow-up results.Result：75.45％myelopathy patients had acute onset. Acutemyelitis accounted for75.45%of acute myelopathy and about half of thepatients（48.19%）were less than five years old；A majority (78.79%) of thepatients demonstrated long segment lesions with5or more segment length.Thetherapeutic efficacy of MP, MP+IVIG and symptomatic treatment hadno difference（P＞0.05）. Most patients （76.57%）had good prognosises,except one had recurrence and was diagnosised NMO. ACTM, who had worse motor function and longer spinal shock than APTM（P＜0.05）,accounted for73.33%of the patients who progressed badly. What’s more,the therapeutic effects of ACTM was also worse than APTM（P＜0.05）.Conclusion：We found that acute myelopathy tend to have acute onsetand acute myelitis was the most common seen. Moreover, ACTM hadworse motor function，longer spinal shock and worse therapeutic effectsthan APTM. The acute myelopathies caused by other different etiologiescan be easily diagnosised by analysising the symptoms, signs, outcomes ofMRI and cerebrospinal fluid of the patients.