The Study Of Myasthenia Gravis Crisis Predict Clinical Assessment

Objective1. Myasthenia gravis crisis predict clinical assessment, so as to better assess risk crisis occurred;2. Through retrospective analysis, through crisis occurred and there was no crisis group score comparison, to discuss the assessment of clinical effect.Results1. Through consulting relevant literature, to develop a comprehensive assessment of MG crisis risk factors (including impact MGC is the most important symptoms, laboratory tests and the related factors).2. After our hospital spleen and stomach disease, respiratory and intensive medicine experts such as audit, combined with the expert opinion, used Delphi method, make a final assessment.3. Use of our hospital from2009to2013hospitalized patients with myasthenia gravis crisis and crisis occurred during salvage statistical analysis of data, find the final conclusion.ConclusionThrough the assessment for reliability and validity of evaluation, it shows that experts motivated that two rounds of expert questionnaire positive index were88.9%,85.7%respectively; Two rounds of expert authority coefficient were0.88,0.88, shows that expert authority is high, the result is reliable; Content validity was0.82, indicating good content validity for scoresheets.Use the scale in our hospital155cases of patients with crisis and score comparison on42patients with crisis, two groups of total score, clinical symptoms, related factors and laboratory indexes between statistical differences (P<0.05), suggesting an important role in crisis forecast, the scale also illustrates the feasibility of the assessment. And42cases of crisis in patients with tracheal intubation and tracheal intubation for statistical analysis, two groups of total score and scores of each part are no statistical significance (P>0.05), So we can not clear grasp the specific time for intubation.Through nearly four years I cure myasthenia gravis patients related data analysis, score higher on admission were higher in patients with crisis, which score in more than16points in patients with crisis probability is81.8%, the risk scores in patients with14points above crisis was76.1%. In terms of length of hospital stay, average number of days occur crisis in-hospital time for31days, the average number of days, there was no crisis in-hospital time for17days, both statistically difference. So the higher score, the crisis the greater the chances, the longer the length of hospital stay. Therefore, when accepts the patient, the physician should be with the patient and family to account the seriousness of the illness, completes the rescue measures, avoid unnecessary doctor-patient conflicts.