P38MAPK Signal Transduction Pathway And Chronic Obstructive Pulmonary Disease

p38MAPK has been found and seperated for more than twentyyears.As a key member of the MAPK family,it has become a hot area ofresearch in recent years. As the further development of research onp38MAPK signal transduction pathway，the mechanism is gradually clear，and we discover that p38MAPK signal transduction pathway plays animportant role in a number of diseases. Additionally，there are more andmore studies about the relationship between COPD and p38MAPK signaltransduction pathway. As one of the most important diseases which causedeaths，COPD is becoming a public health problem which can not beignored.Whereas，the pathogenesis of COPD has not been fully understandyet,and have no effective treatments. A better understand of the p38MAPKsignal transduction pathway in COPD may be critical for the breakthroughof novel therapies. Then, we will emphasis on the potential links betweenp38MAPK signal transduction pathway and COPD，as well as the clinicvalue of COPD treatment.