| Objective: To assess the value of the MRI parameters of uterinefibroid prior to treatment for predicting the therapeutic ablation of uterinefibroid treated with ultrasound-guided high intensity focused ultrasound(USgHIFU).Materials and Methods: To analyze retrospectively the data of152uterine fibroids in94women who underwent USgHIFU from April2012toDecember2013. The T2signal intensity (SI), T2SI ratio, signal uniformity,diffusion-weighted imaging ADC value and the blood supply pattern of theuterine fibroids on pre-treatment MRI was assessed and their relationshipswith ultrasound ablation effect were investigated, and the threshold valuesof the parameters were set up for dividing the treated fibroids andcomparing the non-perfused volume (NPV) ratios of the fibroid after theprocedures.Results: The threshold values of T2SI，T2SI ratio and ADC value ofthe fibroids were200,1.5and1.4×10-3mm2/s. The average NPV ratioswere81.3±16.8%,90.1±13.7%of the fibroids with T2SI≥200and＜ 200,83.6±17.2%and89.7±13.3%of the fibroids with T2SI ratio≥1.5and＜1.5,81.7±18.4%and88.3±14.3%of the fibroids with ADC value≥1.4×10-3mm2/s and＜1.4×10-3mm2/s and80.8±18.8%and89.8±12.8%of the fibroids with hypervascularity and hypovascularity,respectively（P＜0.05). The NPV ratio of fibroids with rich blood supplyand T2SI ratio≥1.5was lower than that of fibroids with less bloodsupply and T2SI ratio＜1.5, less blood supply and T2SI ratio≥1.5orrich blood supply and T2SI ratio＜1.5, respectively(P＜0.05). The NPVratio of the fibroids with T2homogeneous SI≥200was lower than that ofthe fibroids with heterogeneous T2SI≥200, T2heterogeneous SI＜200and T2homogeneous SI <200, respectively (P＜0.05).Conclusions: The MRI parameters of T2SI and its uniformity, ADCvalue and the blood supply pattern could predict the ablation rate of uterinefibroids after USgHIFU treatment, and the ablation efficacy was poor in thefibroids with T2homogeneous hyperintense SI and hypervascularity. |
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