| Objective:To analyze and compare the result of cardiac dual-energy myocardial perfusion with stress/rest myocardial perfusion image, and explore the diagnostic accuracy of myocardial ischemia. Methods:23cases (suspected or known with coronary artery disease) in our hospital were selected, performed dual:source CT dual-energy myocardial perfusion imaging (DE-CTP) and radionuclide myocardial perfusion imaging (SPECT) examination at the same period. Compare myocardial defect in Dual-source dual-energy CT myocardial perfusion image with radionuclide myocardial perfusion image, and evaluate sensitivity, specificity, positive predictive value and negative predictive value of dual-energy CT for the diagnosis of myocardial defect. Results:Among23cases, total of301myocardial segments were obtained by DE-CTP,21segments (9segments in LAD region,4segments in LCX region,8segments in RCA region) of8cases were found with coronary stenosis≥50%. However,20segments (8segments in LAD region,4segments in LCX region,8segments in RCA region) of perfusion abnormalities were found in DECT iodine image, which means there are no significant statistical correlation of two methods. Detected abnormalities of myocardial perfusion of23cases above with DECT abnormal segments of20, regard stress/rest myocardial perfusion image as the gold standard, DECT misjudged5segments; false negative of2segments and false positive of5segments, DE-CTP shows overall sensitivity of99.4%, specificity of85.7%, positive predictive value of90.0%, negative predictive value of99.1%,, Kappa test demonstrates good agreement between the DE-CTP and SPECT Kappa=0.871. Conclusion: Dual-energy dual-source CT myocardial perfusion imaging have high consistency compared with myocardial perfusion radionuclide image; once test could provide all diagnostic information about coronary artery stenosis and myocardial defects or perfusion defect, and also provides an effective way to accurately detect heart disease as a "one-stop-platform". |
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