Prevalence Of Epstein-barr Virus In Tonsillar And Adenoidal Hypertrophy Of Children

Objective To study the Prevalence of Epstein-Barr virus in Chinese children with tonsillarand/or adenoidal hypertrophyMethods We detected the presence of Epstein-Barr virus (EBV) in154tonsil and/oradenoid tissue specimens from112Chinese children with tonsillar and/or adenoidalhypertrophy using real-time fluorescence-based quantitative PCR. Then, we analyzedrelationships between the prevalence of the viruses and other clinicopathologicalcharacteristics of tonsillar and/or adenoidal hypertrophy,And observed the pathological slices ofEBV positive for found proliferation cells.Results EBV infection was detected in19/42(45.24%) tonsil tissues and67.86%(76/112) adenoid tissue specimens (P <0.05). EBV infection was not related to patients’ age,gender, weight,disease course, or nationality,Conclusions We detected EBV in Chinese children with tonsillar and/or adenoidalhypertrophy. Adenoid tissues were more susceptible than tonsil tissues to EBV infection.Moreover, EBV infection could not aggravate snoring in patients with tonsillar and/oradenoidal hypertrophy. EBV-infected cells were found to be B lymphocytes. And theinfected B cells are found in the interfollicular regions of tonsils and adenoids...