The Investigation Of Primary Diagnosis And Surgical Treatment On Bile Reflux Gastritis

Purpose Collected clinical bile reflux gastritis patients. So we further refined bile reflux gastritis symptom diagnosis,understood endoscopic bile reflux gastritis detection rate and found the correlation of popular gastric duodenal cholestasis and bile reflux. During the treatment,we found in diagnosis and pathologic examination and pepsin, detection and the correlation of bile reflux gastritis, giving acid suppression agent and acid suppression agent with mucosal protective agent.After the treatment of 3 weeks, compare the difference between the efficacy of various drugs.Objects and methods We select 7211 patients into a group of objects, which are from 12 urban and rural hospitals’ Digestive outpatient department of Henan from December 2013 to June 2014.We choose 3422 cases of clinic diagnosed patients with bile reflux gastritis, ask them to fill out a detailed questionnaire which including symptoms, signs. According to the survey results, score the symptoms of patients with bile reflux gastritis. Then they’ll have been examined with electronic gastroscopy. From the above two steps to clear the 486 patients were diagnosed as bile reflux gastritis, 200 patients were selected randomly, given oral secretion inhibition and anti acid agents and drugs for the treatment of gastric mucosal protective agent, inhibition of gastric acid secretion drug omeprazole capsules, mucosal protective agents choose aluminum magnesium carbonate, aluminum phosphate gel, ecabet sodium granules and rebamipide tablets, were randomly divided into 5 groups, treatment for 3 weeks. The 188 cases of subjects who before and after treatment should do endoscopic biopsy and pepsinogen check. The reference group selection in natural population of health examination in 200 cases, pepsin and pathological examination for electronic gastroscope.Understand the diagnostic significance of determination of the original biopsy on bile reflux gastritis, pepsinogen and bile reflux gastritis and the relationship between various mucosal protective agents in the treatment of bile reflux gastritis difference.Result Methods questionnaire parallel gastroscopy in 3422 cases, bile reflux gastritis, a total of 483 patients with gastroscopy, bile reflux gastritis, the detection rate of 14.11%, the questionnaire of symptoms, before a few are on the distension of the abdomen in 372 cases, accounting for 77.1%, with 115 cases, accounting for 23.8%, 158 cases of heartburn, 32.7%, acid regurgitation in 123 cases, accounting for 25.4%, 179 cases of depression and anxiety, accounting for 37.1%, 108 cases of constipation, nausea in 56 cases, accounted for 22.4%, accounting for 11.5%, chest pain in 132 cases, accounting for 27.3%. In the survey of 2940 cases of bile reflux gastritis patients, gastroscopy found duodenal cholestasis in 291 people, accounting for 9.9%. 482 cases of bile reflux gastritis gastroscope examination were found in patients with duodenal stasis in 347 people, accounting for 72%. The duodenal bile stasis in patients with bile reflux gastritis prevalence is 23.398 times the normal. Pathology scores no significant differences before and after treatment patients. The decrease of PG2 and bile reflux gastritis with correlation, PG2 and PGR before and after treatment was statistically significant. Given the different mucosal protective agent after 3 weeks of treatment, the control group(omeprazole without mucosal protective agent) efficiency is 77.5%. With mucosal protective agent group the effective rate was 93.8%. The data was statistically significant. There was no significant difference between the mucosal protective agents.Conclusion We found that the bile reflux gastritis of Henan area was higher than that of national statistics. Bile reflux gastritis symptom of several respectively on the distension of the abdomen, mouth pain, heartburn, acid reflux, anxiety, depression, diarrhea, nausea, chest discomfort. Endoscopic observation of bile reflux gastritis patients with duodenal bile stasis is 23.4 times normal, duodenal bile siltation performance on bile reflux gastritis diagnosis flow has important significance.Pepsinogen detection in bile reverse flow. Pepsinogen test in diagnosis of bile reflux gastritis, it is of great significance, has no statistical significance before and after living tissue pathologic examination, combined with gastric mucosal protective agent in the treatment of bile reflux gastritis, curative effect is relatively better acid inhibitors, alone on the gastric mucosa protectant effect has no obvious difference between each other.