BackgroundThe early threatened abortion is a common disease and frequently encountered disease in the early weeks of pregnancy. The incidence of about 20%~25%. The cause of formation of threatened abortion, mainly including embryo factors, maternal factors, father factors, environmental factors and other factors. Threatened abortion is great harm to patients’ physical and mental, modern medicine for treatment of early threatened abortion patients with multi-purpose progesterone preparations, vitamin E and other auxiliary drug is given priority to, but in recent years, with part of the proposed high-dose study abroad side effects of progesterone and its derivatives may affect fetal development ideas put forward, clinicians in the use of progesterone treatment in question concerns how to grasp the dose, resulting in less satisfactory effect. So to find a new method for effective treatment of early threatened abortion is particularly important. This topic through clinical observation, this paper discusses a mentor fetus experience Zhenshu Antai Decoction miscarriage progesterone, vitamin E capsule treatment of spleen and kidney two type of the clinical effect of early threatened abortion, to promote a routine treatment in the early threatened abortion by providing powerful evidence-based basis, in the hope of the future in the treatment of the disease have a better development and protection.ObjectiveThe clinical observation of patients studied by spleen deficiency type 60 cases of threatened abortion, since the proposed clinical experience to explore tutor Zhenshu Antai Decoction (Ligustrum Baizhu Amomum gelatin) threatened abortion patients to spleen deficiency type efficacy to look for the clinical treatment of threatened abortion spleen deficiency type looking for a new way of thinking, in order to verify the necessity of Zhenshu Antai Decoction treatment of threatened abortion, thus widening the conventional treatment of threatened abortion ideas, carry forward Chinese medicine in this superiority in the field to help more patients with early stage survive the pregnancy threatened abortion.MethodA prospective randomized controlled clinical trial design method, January 2014-March 2015 in the spleen and kidney deficiency type 60 cases of threatened abortion patients in our hospital outpatient and inpatient obstetrics and gynecology early randomly divided into treatment group and control group of 30 patients in the control group were treated with oral progesterone capsules, vitamin E capsule therapy, the treatment group received appropriate treatment in the control group, and the addition of Zhenshu Antai Decoction; combined with clinical symptoms and signs were observed before and after treatment scale monitoring of serum human chorionic gonadotropin, progesterone levels change, B-mode ultrasound examination of embryonic development, the situation fluid sac week, parallel clinical symptoms score, the establishment of a database, statistical analysis of data to determine Zhenshu Antai Decoction miscarriage treatment spleen surgery kidney deficiency type threatened abortion is valid.Result1. the spleen deficiency type of threatened abortion patients with early clinical vaginal bleeding, weak waist, abdominal pain, fall as the main performance. Some patients with serum human chorionic gonadotropin in a small amount of vaginal bleeding on the basis of serum progesterone rises slowly, B-Tip inconsistent uterine size and gestational age, embryonic dysplasia, cystic fluid occurs weeks or increase complications; courses After completion, the total treatment group and the control group efficiency of 70.00% and 96.67%, respectively, in the treatment group compared with the control group significantly improved clinical symptoms between the two groups was statistically significant (P<0.05); 2. the treatment group TCM symptoms total score was significantly lower than the control group, the difference was statistically significant (P<0.05); 3.96 hours after treatment, the treatment group and the control group, serum human chorionic gonadotropin (β -HCG), progesterone (PG) than before treatment were significantly increased, the difference was statistically significant (P<0.05), and 96 hours after treatment, the treatment group β-HCG, PG rise compared with large control group, the difference was statistically significant (P<0.05); 4. weeks after treatment bursa effusion significant improvement compared with the control group, the difference was statistically significant (P<0.05); 5. monitoring vital signs of patients before and after treatment showed no abnormalities;Zhenshu Antai Decoction Joint progesterone soft capsules, vitamin E capsule therapy None of adverse reactions.ConclusionZhenshu Antai Decoction miscarriage progesterone, vitamin E capsule therapy spleen deficiency type threatened abortion in pregnant women to alleviate symptoms, elevated serum human chorionic gonadotropin, progesterone levels, improve fetal development of the situation and clinical evaluation was superior to clinical application of progesterone alone, vitamin capsules, better efficacy of integrative medicine. Therefore, Chinese medicine treatment of threatened abortion would be an ideal choice for satisfying assured safety for patients survive the pregnancy escort. |