| BackgroundTo observe the clinical effect of the formula made of "wu ling powder" and the "bu yang huan wu tang", based on "huo xue li shui" method, by analyzing the EI index, biochemical indicator, and so on.MethodsAccording to the inclusion criteria and the exclusion criteria, the patients with brain tumor complicated with cerebral edema were randomly divided into treatment group and control group with two groups.. To meet the requirements of patients in the implementation of surgical resection of brain tumor. Operation immediately after the head CT examination, blood biochemical index, collecting EI, electrolytes and renal function results. The control group was treated with routine western medicine, and treated with 20% mannitol as the dehydration agent.. The treatment group on the basis of the control group, with "huo xue li shui" under the guidance of the "Wuling powder" and "Buyang Huanwu Decoction" is based on the localization of cutting compound traditional Chinese medicine decoction (oral or nasal feeding). Repeat the above examination as a observation point for 10 days.. After the end of therapy, EI index of the two groups of patients, electrolytes, renal function, symptoms and KPS score index changes and the income data were statistically correlated analysis, evaluation of the effect of two kinds of treatment.Result1. Using the method of "huo xue li shui" under the guidance of "Poria five powder" and "Buyang Huanwu Decoction" as the foundation of the CD to a traditional Chinese medicine compound with mannitol to achieve the effect of better treatment of cerebral tumor of brain edema.The control group and the treatment group before and after treatment EI index, found that the effective rate of the 70% groups were more than two, to a certain extent, two treatment regimens can play the effect of brain edema after brain tumor surgery. After treatment, the patients in the two groups of the EI index were compared found treatment effective number, effective number were significantly higher than that of the control group, by the Wilcoxon rank sum test. It is found that the difference was statistically significant (P< 0.05), indicating that the treatment group curative effect surpasses the control group.2. Using the method of "huo xue li shui" under the guidance of "Wuling powder" and "Buyang Huanwu Decoction" as the foundation of the CD and the traditional Chinese medicine combined with mannitol in treatment of cerebral tumor of brain edema than the simple use of mannitol party less electrolyte imbalance (hypokalemia, hyponatremia hyponatremia).Numerical comparison numerical comparison between the numerical comparison between the numerical comparison control group and the treatment group before treatment, serum potassium, serum sodium had no statistical significance (P > 0.05), indicating that the two groups before treatment, serum potassium, serum sodium differences; after treatment two groups of serum potassium, serum sodium is also no statistical significance (P> 0.05), indicating that the two groups before treatment, serum potassium, serum sodium difference; treatment group before and after treatment of serum potassium, serum sodium had no statistical significance (P> 0.05), indicating that the treatment group before and after treatment, serum potassium, serum sodium had no obvious change, but the control group before and after treatment, serum potassium, serum sodium was statistically significant (P<0.05), indicating that the treatment group before and after treatment, serum potassium, serum sodium change, and showed after treatment compared with before. By chi square test were performed to hypokalemia, hyponatremia in patients with hyperlipidemia number after treatment in the two groups and between the two there differences (P< 0.05), indicating that the treatment group than in the control group is less electrolyte disorder caused by.ConclusionsGuide 1 "huo xue li shui" method of the Chinese herbal compound "Poria five powder" and "positive also five soup" as the basis of a cut with mannitol in the treatment of brain edema of brain tumor (phlegm and blood stasis) has better curative effect, can improve the clinical curative effect; 2 "huo xue li shui" under the guidance of the law "five water chestnutsdisperse" and "Yang also five soup" as the basis of cut and compound Chinese medicine can reduce the use of mannitol caused by electrolyte disturbances occurred; 3 "huo xue li shui" method under the guidance of the "five water chestnutsdisperse" and "Yang also five soup" as the basis of the CD from traditional Chinese medicine compound with mannitol in the treatment of brain tumors and brain edema (phlegm and blood stasis syndrome) in the process, did not affect the treatment of patients with BUN, no significant renal toxicity, the clinical application is safe. |
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