| Purpose:Acupuncture combined with Gexiazhuyutang subtraction, both methods of treatment of oral mifepristone stagnation type adenomyosis, comparing two treatments was observed for patients with dysmenorrhea adenomyosis points, uterine size, CA125 values The effects and compare overall clinical efficacy in the treatment of adenomyosis, drug side effects difference. Methods:Select study 70 cases met the diagnostic criteria of this study were randomly divided into treatment group and control group, some patients during treatment or drop out due to various reasons, the termination, leading to the final completion of the study and statistical analysis included only 60 cases cases. Treatment group received acupuncture combined Gexiazhuyutang subtraction, to 10 days before menstruation began acupuncture treatment, acupuncture and acupuncture acupoints: Qihai, Guanyuan, Zhongji; Taichong, Xuehai, Hegu; Sanyinjiao and Zusanli. Acupuncture once a day, after the gas plus TDP; traditional Chinese medicine to treat law Gexiazhuyutang based side, combined with the physiological changes in the menstrual cycle, blood circulation, eliminate disease Sanjie, gas pain is. The control group were given oral mifepristone, in the first day of menstruation to begin treatment, 1 time/day, each 12.5mg. Three menstrual cycles for a course of treatment, continuous a course of treatment. During the medication a adverse drug reaction cases was observed between the two groups of patients;After a course of treatment, the third menstrual cycles, the total effect was observed between the two groups of patients in clinical treatment, as well as before and after the treatment of dysmenorrhea points, uterine size, changes in serum CA125 values, the use of the data results SPASS18.0 statistical software recorded for statistical analysis. Result:(1) Side effects of treatment group and control group patients during the medication were significantly different drugs(P<0.01), side effects of drug treatment group was significantly lower than the control group situation.(2) The treatment group and the control group, the total efficiency of 90%, 86.67%, respectively, between the two groups overall clinical efficacy group, no significant difference(P = 0.89> 0.05), the total effect of two clinical considerable;(3) Comparison of in the treatment group before and after dysmenorrhea integration group, a significant difference(P<0.05), comparing within dysmenorrhea integration group in the control group, a significant difference(P<0.05), between dysmenorrhea integral group after treatment There were significant differences(P=0.03<0.05), the treatment group than the control group;(4) Treatment groups utero large group before and after treatment were significantly different(P<0.05), treatment group relatively large group before and after treatment in the womb, there is a significant difference(P<0.05), uterine relatively large group after treatment, no significant difference(P=0.09>0.05), the two groups was quite uterine size change;(5)Compare within treatment group before and after treatment CA125 value group, a significant difference(P<0.05), comparing within the control group before and after treatment CA125 value group, a significant difference(P<0.05), between CA125 valuesgroup after treatment There were significant differences(P=0.02<0.05), the treatment group than the control group; Conclusion:(1)Acupuncture combined with Gexiazhuyutang subtraction, combined pathogenesis and physiological changes in the menstrual cycle, blood circulation, eliminate disease Sanjie, qi rules for the treatment of pain, treatment of blood stasis type adenomyosis disease, and current Western medicine clinical reports proven drug mifepristone compared to the total clinical efficacy rather, can significantly improve the symptoms of dysmenorrhea, lower CA125 values, reduce the size of the uterus, where integration and CA125 values change dysmenorrhea, treatment group than the control group, but no hot flashes after taking mifepristone-induced vaginal spotting, weight gain and other side effects of drugs, with better clinical efficacy.(2) Acupuncture combined with Gexiazhuyutang Treating blood stasis type adenomyosis, superior clinical efficacy of oral mifepristone group, not only to make the clinical symptoms have been alleviated, but also to improve the lives of patients quality, fully embodies the characteristics and advantages of the dialectical theory of governance ideology, its mechanism of action is worthy of further study, treatment worthy of clinical use. |
PDF Full Text Request