Antimicrobial Agent In Pharmaceutical Preparations (Preservative) Effectiveness Measurement And Standards Research

Antibacterial effect of test method for determining the inhibitory potency tests, more specifically is that of determining activity of antibacterial agent in pharmaceutical preparations, in order to evaluate the inhibiting effect of pharmaceutical preparations. Bacteriostatic effect tests also can be used to guide enterprises in developing drugs for antibacterial agents (preservatives) is OK. Pharmaceutical preparations containing bacteriostatic agents (preservatives), enterprises in the development stage must be identified in the drug antimicrobial agents (preservatives) antibacterial effect and protect public safety. Effects of antibacterial effect of the size of the container, such as the influence of the material, the shape of the container. If the original packaging of the product can meet the test criteria, then the test can be tested by five former test bottle or can meet the conditions of sterile bacteriological container with lid (no adsorption). Each container after inoculation with a standard liquid of prepared, mixed and inoculum of the fungus cannot exceed the product install 0.5%-1.0%. Be prepared for test samples stored at 20 degrees to 25 degrees in the incubator, respectively,7-day,14-day and 28-day microbial counts in samples, effects of initial plus the amount and result analysis.The purpose of this research is the establishment of 5 kinds of chondroitin sulfate eye drops containing bacteriostatic agents (preservatives) typical varieties of drugs bacteriostasis effect of method and test of its antimicrobial effect for the CHP and other standard scientific formulation preservatives control standards and appropriate test methods to provide evidence. Through the study of this subject, chondroitin sulfate eye drops and preservative compound Kok acid ester cream adds a standard provides a strong reference. As well as our medication safety knocked the alarm. This topic selected finished drug dosage mixed antibacterial agents. Some bacteriostatic agent dosage of drugs is not enough, not up to the antimicrobial effect. Bacteriostat bacteriostatic effect of some drugs in accordance with Pharmacopoeia, but there are risk of overdose preservatives added.