A Case Report Of Peutz-Jeghers Syndrome And Literature Review

Objective:To explore the epidemiology, clinical characteristics, imaging tests, differential diagnosing, treatment, follow-up visit of Peutz-Jeghers Syndrome(referred to as PJS). so as to improve the level of diagnosing treatment and the follow-up of consciousness, to reduce the occurrence of cancer.Methods:The clinical data of one patient suffered from PJS were retrospectively analyzed, and the literature were reviewed.Data:A male adolescent patient, who had intermittent nausea and sickness for more than two months, vomits yellow liquid. His oral lips, fingertip, end of the toes are covered with visible smooth black pigment spots which do not mix together.Interventions:To carry out the routine examination and chest X-ray, abdominal X-ray, electronic gastroscopy, electronic colonoscopy, the entire digestive tract barium meal and pathological examination, so as to make the definite diagnosis. Meanwhile, supportive treatments including prohibiting drinking water, fasting, gastrointestinal decompression, keeping water, electrolyte and acid base balance, nutritional support to, and symptomatic treatment were used. Give surgical operation after the comprehensive analysis combined with test results, close observation and follow-up.Results:Abdominal X-ray showed:abdominal part of the intestinal is inflatable. Electronic gastroscopy showed:gastric polyps. Electronic colonoscopy showed:colonic polyps. The entire digestive tract barium meal showed:the jejunum were markedly dilated under Trietz ligament, considering the incomplete intestinal obstruction, please combined with clinical. The postoperative specimens of intestine were sent for pathological examination. Pathological examination showed:(jejunum) biopsy specimens were consistent with PJS (Peutz-Jeghers polyps).Conclusion:Many PJS patients are hospitalized for intestinal obstruction or incomplete intestinal obstruction with vomiting, sickness, abdominal pain and abdominal distension. A considerable portion of patients with family history visible smooth black pigment spots which do not mix together on oral lips, fingertip, end of the toes, perineum and so on. Combining with the comprehensive judgment of gastrointestinal endoscope and pathological examination results, the accuracy of diagnosis can be improved. In addition, much attention should be paid because of the high recurrence rate of PJS.