| ObjectiveTo summarize patients between January 1,2013 and March 31,2013 in Chinese PLA general hospital who are more than 60 years old, establish the hematologic reference intervals (RIs) in the elderly. And to study the prevalence and the cause of anemia in the elderly, to provide a theoretical basis for the treatment and prevention of anemia.Methods1. All data of patients admitted to Chinese PLA general hospital between January 1, 2013 and March 31,2013 were collected. Patients were stratified according to different age groups, then establish the hematologic RIs.2. To further analysis the prevalence of anemia in the elderly, and summarize the cause of anemia.Results1. ①Between January 1,2013 and March 31,2013,4682 patients who are more than 60 years old were admitted to the Chinese PLA General Hospital, of which,2907 male and 1775 female. The overall mean age was 72.34 years old. ②The RIs of Hb in the reference population with respect to age(ranges of 60～69,70～79,80～89 and 90-years) were 116-171, 111-167,106-162,108-164g/L for males, respectively, and 108-152,106-153,102-151, 108-144g/L for females, respectively. ③The RIs of Hb were 110-168 g / L for male, 107-152g/ L for female. Both in the male and female, Hb decreased along with the age increased. ④There was a significant difference of Hb, RBC, Hct, MCV, MCHC, PLT levels in different gender and age group(P<0.05).There was no significant difference of MCH in different age group(P<0.05),but there was a significant difference in gender(P<0.001).There was a significant difference of WBC, N, L, M, E, B levels in different age group(P<0.05), but there was no significant difference in gender(P>0.05).2. ①Between January 1,2013 and March 31,2013,10307 patients who are more than 60 years old were admitted to the Chinese PLA General Hospital, of which,6514(63.2%) male and 3793(36.8%) female. The overall mean age was 72.05±9.07 years old. The ordinary were 8733 (84.7%) cases,1574(15.3%) cases were cadre. The hospitalization were 7314(71.2%) cases,2966(28.8%) cases were outpatient. ②According to WHO criteria (male <130g/L, female<120g/L), in male,2474(38.0%) cases were anemia, the prevalence rate of 29.2-62.9%; in female,1369(36.1%) cases were anemia, the prevalence rate of 29.4-57.5%. According to " Diagnostic and curative standard of hematology " Zhang Zhi-nan, Version 3 (male<120g/L, female<110g/L), in male,1545(23.7%)cases were anemia, the prevalence rate of 18.6-41.8%; in female,867(22.9%) cases were anemia, the prevalence rate of 18.1-41.3%. According to 2.5 percentile, in male,1098(16.9%) cases were anemia, the prevalence rate of 16.3-25.0%; in female,780(20.6%) cases were anemia, the prevalence rate of 16.8-40.0%.③In male and female, mild anemia accounted for 88.22%> 84.08%,respectively.④The prevalence of anemia increased with the age increased. There was no significant difference in different gender and category (P>0.05).Compared with outpatient, the prevalence of anemia in hospitalization was significant high (P＜0.01).⑤ Of 1767 patients were analyzed, Of which,1081 (61.2%) male and 686 (38.8%) female. The main cause of anemia could be divided into three categories:1) 336(19.0%) cases of nutritional anemia, including 225(12.7%) cases of iron deficiency anemia,111 (6.3%) cases of folate, and/or vitamin B12 deficiency anemia.2) 612 (34.6%) cases of chronic disease, including 241 (13.6%) cases of chronic kidney disease,371 (21.0%) cases of chronic inflammatory diseases.3) 819(46.4%) cases of unexplained anemia.Conclusion1. Both in the male and female, Hb decreased along with the age increased. There was a significant difference of Hb, RBC, Hct, MCV, MCHC, PLT levels in different gender and age group. There was no significant difference of MCH in different age group, but there was a significant difference in gender. There was a significant difference of WBC, N, L, M, E, B levels in different age group, but there was no significant difference in gender.2. The prevalence of anemia increased with the age increased. The prevalence of anemia varied with the ways of treatment, but there was no significant difference in different gender and category. In respect of etiology, unexplained anemia topped the list, and then chronic disease, nutritional anemia was the last. |
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