Preparation And Analysis Of Relevant Factors Of The Hour-specific Bilirubin Nomogram Of Uighur And Han Neonates

Objective:To design the hour-specific bilirubin nomogram of healthy near-term and term newborns of Uighur and Han in the first 120 hours after birth, anlysis of relevant factors, compare the trends of the hour-specific bilirubin and the incidence of hyperbilirubinemia of Uighur and Han neonates,provide clinical work with material.Method:Choosing the healthy Uighur or Han infants(gestational age>35weeks and birth weigtht≥2000g)born in the obstetrics of First Affiliated Hospital of Xinjiang Medical University and Urumqi MCH, in February, April, June, August, October, December of 2013.The potential cases(gender, gestational age, mode of delivery, birth weight, feeding patterns, first feeding time, meconium time, premature rupture of membranes, cephalohematoma) of neonatal jaundice were recorded detailedly. Transcutaneous bilirubin (TCB)was measured in 3-5 day after birth by the JM-103 transcutaneous bilimeter, twice per day. Each case had 6 measurements at least. Calculating the TCB percentile of each period respectively (P40,P75,P95), designing the nomogram and analysis the influence of relevanted perinatal factors of hyperbilirubinemia with the univariate χ2 test and multivariate Logistic regression analysis, finding the relevant factors.Results:The plateau was 92-120h of age in the study; At the same time, the TCB percentile of the neonates of the study(P 新 140,75,95)) were higher than the TCB percentile of the neonates of Yu zhang-bin et al’s study(P 国内 40,75,95)),the TCB percentile of the Han neonates of the study P 汉 (40,75,95) were higher than P 国内 (40,75,95) and the TCB percentile of the Uighur neonates of the study P维 (40,75,95), and P 国内(40,75,95）were higher than P维(40.75,95)； The rate of P95 rised faster than P75 and P40； The incidence of hyperbilirubinemia of Han neonates was higher than Uighur neonates, χ2=71.523, P< 0.01, the difference was statistically significant; Premature, esarean, breast feeding, Han were the unattached risk factors of hyperbilirubinemia. Conclusion:Hour-specific nomogram reflected the trends of the bilirubin levels and had certain assessed value of hyperbilirubinemia; The bilirubin of Uighur and Han neonates rised with the growth of age, and the hour-specific bilirubin of Han neonates rised quicker than Uighur neonates;The incidence of hyperbilirubinemia of Han neonates was higher than Uighur neonates; Premature, cesarean, breast feeding, Han,first feeding time, meconium time were the independent risk factors of hyperbilirubinemia.