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Studies On The Extraction Process And Quality Control For Lumbar 2 Capsules

Posted on:2016-03-07Degree:MasterType:Thesis
Country:ChinaCandidate:G L XiaoFull Text:PDF
GTID:2284330464956470Subject:Drug Analysis
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Lumbar 2 capsule was made by Rhizoma astilbes Chinensis. Cibotium barometz(L.)J.Sm., Gentiana macrophylla Pall., Corydalis decumbens(Thumb.)Pers., Sinapisalba L., Phryma leptostachya L Strychnas nux-vomica L.. But h us martensii Karsch. Scolopendra subspinipes mutilans L., Koch Bungarus mnlticinctus mnclticinctusB lyth, Manis pentadactyla Linnaeus. It was made by 11 of traditional Chinese medicine. It was to treat the patient for lumbar disease of TCM clinical experience prescription, after many years of clinical observation and treatment of lumbar pain had obvious effect, the lumbar 2 prescription preparation technology was optimized by this experiment. It set feasible for lumbar 2 capsule quality control.Lumbar 2 capsule technology was designed by L9 (34) orthogonal. Herbs was extracted by water feflux, according to the frequency, extraction time, ratio of water, with lumbar 2 capsules medicinal herbs extract rate and effective ingredients bergenin content as an index. The result was analyzed with comprehensive evaluation method to select the best extraction process. Lumbar 2 capsule of quality control was by Thin layer Chromatography (TLC), to identify Rhizoma astilbes Chinensis, Corydalis decumbens(Thumb.)Pers. Manis pentadactyla Linnaeus and so on in lumbar 2 capsule of traditional Chinese medicine; by High performance liquid chromatography (HPLC) was developed for the determination of bergenin content as quality control.
Keywords/Search Tags:Lumbar 2 capsule, The orthogonal experiment, TLC, HPLC, Exteaction process, Quallty control
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