Develop. The Laojun Shengbai Capsule Development And Quality Standards

The prescription of Laojunshengbai capsules, consists of eight medicinal herbs- ASTRAGALUS ACANTHOPANAX POLYGONUM ANEMARRHERA ZIZIPHUS etc. It was experimented and developed on the basis of clinical practice of doctor of traditional Chinese medicine. It belongs to a new form of the type medicine. --3-- According to the chemical properties and dosage of the herbal medicine, the decoction were improved and made CAPSULES in order to overcome it抯 shortcomings of herbal medicine. Conditions for the extraction were studied by orthogonal experimental design as guided by the content of ASTRAGALIN present in the extract. Provides a scientific basis for studying on extraction process of Laojunshengbai capsules; The content of Aastragalin , the main active principle in the granule derived from ASTRAGAL]IN was assayed by TLCS and the presence of ACANTHOPANAX POLYGONUM ANEMARRHERA ZIZIPHUS etc were identified by TLC. The formulation of a standard for the quality control of Laojunshengbai capsules was studied. Provides a certain evidence for controlling the quality of Laojunshengbai capsules. We have gone into operation of medium-sized scope for Laojunshengbai capsules. We investigated the quality of the stability for Astragalin compound capsules. --4-- As the main active principle in the Astragalus compound capsules Astragalin could elevate leukocyte count. More and more Leukcyte come to body. The second active principle ACANTHOPANAX and POLYGONUM contributes to increase the amount of blood. The third active principle ANEMARRHERA ZLZIPHUS were antipyretic and antidote. ZIZIPHUS etc were the fourth active principle. They build up brains. The extracted techniques of the Laojunshengbai capsules were determined by orthogonal design method by assay of Astragalin in the extraction. The optimal technical parameters were as follow: using 6times animount of 60% alcohol as extracting solvent to reflux for 2hours and twices. The extracted techniques of the Fructus ligustri were determined by orthogonal design method by assay of Schizandrin in the extraction. The optimal technical parameters were as follow: using 8times ammount of 80% alcohol as extracting solvent to reflux for 2hours and twices. Conditions for the extraction were studied by orthogonal --5-- ~+ flfl(j~ experimental design as guided by the content of Berberine vulgaris present in the extract. The optimum condition for the extraction of the other six traditional Chinese medicine such as ANEMARRI-IERA was to decoct medicinal herbs twice 2h and eightfold. There is some sediment in the decoction medicinal herbs by 60% alcohol. Using pressure reducer to dry the drug, In order to control the quantity of the main active principle in the granule derived from Laojunshengbai capsules was assayed by TLC to break parts ASTRAGALIN. The presence of ACANTHOPANAX POLYGONUM ANEMARRHERA ZIZIPHUS etc Chinensis were indentified by TLC. The content of Astragalin the main active principle in the granule derived from ASTRAGALUS was assayed by inC. the greatest wavelength of A...