Application Of Diffusion Weighted Magnetic Resonance Imaging In The Differentiation Between Spinal Tuberculosis And Spinal Metastases

Objective:This study proposed to analysis the evaluate the clinical value of magnetic resonance imaging (MRI), MRI combined with magnetic resonance diffusion weighted imaging (MR-DWI) in the differentiation between spinal tuberculosis and spinal metastases.Methods:Materials and methods:We collected the data of magnetic resonance images of the histopathological examination confirmed the diagnosis of spinal lesions were 100 (60 tuberculosis of spine spinal metastases,40), which contains both conventional magnetic resonance, diffusion-weighted magnetic resonance imaging data 50 (30 copies of tuberculosis of spine spinal metastases,20), spinal tuberculosis is set as the case group, spinal metastases is set as the control group. Combining the analysis diagnosis of results of MRI and DWI data with pathological with x2 to analysis the evaluate the clinical value of MRI, MRI combined with MR-DWI in the differentiation between Spinal Tuberculosis and spinal metastases. According to magnetic resonance imaging features of region of interest ROI (region of interest, ROI) measured the diffusion coefficient of sensitivity (b value) of spinal tuberculosis and spinal transfer tumor patients (next to the bone marrow edema, bone destruction and vertebral lesions) and the lesion area adjacent normal vertebral body of apparent diffusion coefficient (apparent diffusion coefficient, the ADC values of mean value. The differences of ADC values of spinal tuberculosis and metastases normal vertebral body and lesion area (bone marrow edema, bone destruction and vertebral adjacent lesion tissue) were analyzed by using statistical software SPSS 19.0.Results:1.Magnetic resonance imaging in the diagnosis of spinal tuberculosis sensitivity of 87.5%, specificity of 89.4%.2.The sensitivity and specificity of conventional MRI combined with MR-DWI for diagnosis of spinal tuberculosis were 92.4% and 94.6%, respectively.3.When B=500s/mm2, spinal tuberculosis and metastasis tumor of the average ADC value is compared in the bone marrow edema, destruction of vertebral bodies and intervertebral side abscess respectively(0.65±0.10)×10-3mm2/s VS (0.62±0.13)×10-3mm2/s; (0.72±0.13)×10-3mm2/s VS (0.66±0.13)×10-3mm2/s; (0.92±0.14) ×10-3mm2/s VS (0.44±0.10)×10-3mm2/s. lesions of various kinds the average ADC value difference has statistical significance (P<0.05); spinal tuberculosis and metastasis tumor adjacent normal vertebral average ADC value (0.63±0.12)×10-3mm2/s VS (0.60±0.15)×10-3mm2/s. Between the two is not with statistical significance (P>0.05). The sensitivity and specificity of diagnosis of spinal tuberculosis were 88.7% and 90.7%, respectively.Conclusion:1. The sensitivity and specificity of conventional MRI combined with MR-DWI in the diagnosis of spinal tuberculosis are higher.2. Magnetic resonance diffusion weighted imaging is the more reliable and reliable noninvasive examination for diagnosis of spinal tuberculosis than conventional magnetic resonance imaging. MR-DWI has reliable clinical application in the differential diagnosis of spinal tuberculosis, spinal tuberculosis and spinal metastases.