Study On Quality Of Life And Its Influencing Factors Of Children With Congenital Anorectal Malformation

Objective To investigate quality of life and the influencing factors of children with congenital anorectal malformation(CARM), so as to provide evidence for developing effective interventions and improve QOL of children with CARM.Methods The Chinese version of Pediatric Quality of Life Inventory Version 4.0(Peds QLTM4.0) Generic Core Scales was applied to assess quality of life. Follow-up survey was carried out among 100 children aged at 2 and 5 years old. To compare the scores of QOL between CARM children and healthy children and analyze its influencing factors on QOL of children with CARM.Results(1) QOL scores of the emotional function among CARM children aged at 2 years old were higher than those of healthy children,there was statistic difference between the two groups(P<0.05). QOL scores of the physiological function, social function, and total scale among CARM Children aged at 2 years old were higher than those of healthy children, but there was no statistic difference(P>0.05).QOL scores of the physiological function, emotional function, social function, school performance and total scale among CARM Children aged at 5 years old were higher than those of healthy children, there was statistic difference between the two groups(P<0.05). The difference of QOL scores in emotional function was significantly. QOL scores of the 4 dimensions and total scale was compared between CARM Children aged at 2 and 5 years old, but there was no statistic difference(P>0.05).(2) The physiological function, emotional function, social function, school performance and total scores of Children with CARM aged at 5 years old self-report were higher than those of caregiver proxy-report, but there was no statistic significant difference between the two groups(P>0.05). QOL scores of the physiological function,emotional function,social function,school performance of healthy children at the same age self-report were higher than those of caregiver proxy-report,there was statistic significant difference(P<0.05).(3) The results of ANOVA among CARM children aged at 2 years old showed that the clinical classification, bowel disorders and family residence have different influence on QOL scores of the 4 dimensions and total scale(P<0.05),except for the gender, primary caregiver, paternal education, maternal education, paternal occupation, maternal occupation and family income(P>0.05).The results of ANOVA among CARM children aged at 5 years old showed that the clinical classification, bowel disorders and maternal education have different influence on QOL scores of the 4 dimensions and total scale(P<0.05),except for the gender, primary caregiver, family residence, paternal education, paternal occupation, maternal occupation, family income(P>0.05).(4) The results of multiple stepwise regression model among CARM children aged at 2 years old showed that the major influence factor of QOL scores in physical function was family residence and bowel disorders(P<0.05), the major influence factor of QOL scores in social functioning was bowel disorders(P<0.05), the major influence factor of the total scores was bowel disorders and family residence(P<0.05).The results of multiple stepwise regression model among CARM children aged at 5 years old showed that the major influence factor of QOL scores in physical function was maternal occupation and clinical classification(P<0.05), the major influence factor of QOL scores in emotional functioning was bowel disorders(P<0.05), the major influence factor of QOL scores in social functioning was clinical classification and bowel disorders(P<0.05), the major influence factor of QOL scores in school performance was maternal occupation(P<0.05), the major influence factor of total scores was bowel disorders and clinical classification(P<0.05).Conclusion(1) QOL of CARM children aged at 2 and 5 years old were higher than those of healthy children,especially in emotional function.(2) Family residence and bowel disorders have effect on QOL of children with CARM aged at 2 years old. Maternal occupation, clinical classification and bowel disorders have effect on QOL of children with CARM aged at 5 years old.