The Correlation Analysis Between The Assessment Of DBCD Donors With Their Organ Protections And The Postoperative Graft Recovery Of The Corresponding Liver And Kidney Recipients

Objective To analyze the correlations between the state ofthe DBCD donors and the graft functions recovery of the correspondingliver and kidney recipients. Methods We retrospectively analyzed theassessment information and the organ protections of the12DBCD donorsbetween August2010and November2013in the organ transplantationcenter in Sichuan Provincial People’s Hospital,the correspondinginformation include sex, age, the cause of brain death, medical history,ICU period, WIT, Cr, ALT, AST, TBIL, Alb, SBP, DBP, the count ofWBC, HGB, PT, APTT, FIB, INR, the level of blood glucose, the pH ofABG, K+, Na+, all data are recorded on the last day before the operation.We also collected the clinical information of the12liver recipients andthe24kidney recipients who have received the organs from the DBCDdonors. The information of the liver recipients includes sex, age,diagnosis, the WIT of the liver, the CIT of the liver, LOS(length ofstay)after the transplantation, the ALT of7days after the operation, theALT of14days after the operation, the ALT of21days after theoperation, the TBIL of7days after the operation, the TBIL of14daysafter the operation, the TBIL of21days after the operation, the INR of7days after the operation, the INR of14days after the operation, the INRof21days after the operation, the length of staying in ICU, the length ofusing breathing machine after operation, the total Alb of transfusion afteroperation, the total plasma of transfusion after operation, the total RBC oftransfusion after operation. The information of the kidney recipientsincludes sex, age, diagnosis, the WIT of the kidney, the CIT of the kidney,LOS(length of stay)after transplantation, the Cr of3days after the operation, the Cr of7days after the operation, the Cr of14days after theoperation, the Cr of leaving hospital.,whether the AR/DGF/pulmonaryinfection occurred after the operation. The analytical method: Weorganized the data of the DBCD donors to the liver recipients and thekidney recipients respectively, the independent variable is the data of theDBCD donors, the dependent variable is the data of the liver recipientsand the kidney recipients, checking all data include “4features”, try tomodel the correlations and analyze them by using multiple linearregression or Logistic regression, we used SPSS19.0software tocomplete the statistical analysis, the data which can be built models andthe corresponding P＜0.05shows statistical significance. Results Theresults of our study in the correlations between the state of the DBCDdonors and the graft functions recovery of the corresponding liver andkidney recipients are below:1. The number of the recipients who gotPNF after the liver transplantation is1(1/12,8.3%), and for the DGFafter the kidney transplantation, it is11(11/22,50%).2. In the criterion ofthe study, WIT, CIT, HGB, FIB, Alb, Cr, the data before could notinfluence the postoperative recovery of the corresponding liver andkidney recipients.3. The data that could be thought relevant in statistic(P﹤0.05) to the postoperative recovery of the corresponding liver andkidney recipients in the study: ICU period, liver function (ALT/AST),SBP, PT,INR, blood glucose level, electrolyte(Na+), can influencethe postoperative recovery of the corresponding liver and kidneyrecipients.4. Age, cause of brain death, DBP, APTT, the pH of ABG,TBIL, the count of WBC are also thought relevant to the postoperativerecovery of the corresponding liver or kidney recipients. Conclusions1.DBCD donors that have been actively taken the correspondingprotective measures and accurately assessed can be the suitable donors which are fit for the situation in China.2. The possibility of DGF afteroperation in DBCD kidney recipients is quite big in our study, but all ofthe patients can be well cured by dialysis and other corresponding cures.The urine volume and the Cr, the dynamic monitor of them and thecontrolling in a scientific range of them take a very important role.3. Thepossibility of the PNF after operation in DBCD liver recipients is quitesmall in our study; the PNF could be nearly avoided.4. The data of theassessment in DBCD donors below: WIT, CIT, HGB, FIB, Alb, Cr, theirranges are the most fixed, they are the minimum control and the mostimportant in all of the data.5. The data of the assessment in DBCDdonors below: ICU period, ALT,AST,SBP, PT,INR, blood glucose level,K+, Na+, their ranges are quite fixed, they are a little controllable andquite important in all of the data. So we should dynamically monitor themand control them in a scientific range, it is good for the postoperativerecovery of the corresponding liver and kidney recipients.6.The data ofthe assessment in DBCD donors below: age, cause of brain death, DBP,APTT, the pH of ABG, TBIL, the count of WBC，in all of the data, theyhave the maximum ranges and controlling, and they are the minimumimportance.