Study On Relationship Between Blood Stasis Syndrome And Calcium-phosphorus Metabolism Disorder In Maintence Hemodialysis

Objective:Studies have shown that calcium and phosphorus metabolism and blood stasis syndrome were widespread in maintenance hemodialysis (MHD) patients,and both are closely related to the MHD patients with cardiovascular disease.This study was to investigate the relationship between calcium and phosphorus metabolism in MHD patients with blood stasis-syndrome,investigate MHD patients with abnormal calcium and phosphorus metabolism-occurs in the role of blood stasis,prevention and treatment of cardiovascular disease in patients with MHD provide a theore tical basis.Methods:120patients in our hospital MHD combines four diagnostic reference Chen Keji "blood stasis syndrome diagnostic criteria and quantitative score sheet " for patients with bolld stasis syndrome diagnosis and score to determine the extent of its blood stasis-syndrome.All patients included in the monthly check once blood.liver and kidney function,blood lipids,electrolytes (serum calcium,serum phosphorus,etc.),calculated phosphorus product,a three-month investigation iPTH,25-hydroxy vitamin D (calcitrilo avoid shock bolld during treatment),all clinical outcome measures by the hospital laboratory using a Hitachi7170automatic biochemical analyzer,whichever is3times the average of the results of blood.Patients were analyzed to understand the metabolism of calcium and phosphorus According to2007NKF K/DOQI targer.Finally,the use of statistical method (t-test,correlation analysis,multiple logistic regression analysis) to analyze the relationship between blood stasis syndrome.Results:1, hemodialysis patients with blood stasis occurrence:120hemodialysis patients,22cases (18.3%) non-BSS group, BSS group98cases (81.7%), which accounted for mild BSS group45.9%(55cases), severe blood stasis syndrome group accounted for35.8%(43cases); and stasis of blood stasis group scores were significantly higher than non-BSSgroup (46.51±23.27vs12.88±2.76, p<0.05.).2, patients with major syndromes of traditional Chinese medicine and BSS group mainly QDBS (48cases), followed respectively, phlegm and blood stasis syndrome (12cases), Hanning blood stasis syndrome (8cases), toxic heat blood stasis syndrome (4cases), the proportion of blood stasis syndrome (3cases) accounted for less. the proportion of blood stasis syndrome (three cases) accounted for less. BSS group and non-BSS age group (61.42±9.16vs.38.54±12.23), systolic blood pressure (168.25±18.63vs.131.32±19.40), Alb (40.03±5.11vs.32.57±3.89), LDL-C (.3.43±0.72vs2.12±0.83) compared to a statistically significant difference (p<0.05); between the two groups of gender, diastolic blood pressure, duration of dialysis, Hb, Scr, TC, TG difference was not statistically significance (P>0.05).The presence of calcium and phosphorus metabolism in4,106patients (88.3%) patients with abnormal (failed to meet the K/DOQI target), mainly as phosphorus, calcium-phosphorus-product, parathyroid hormone increased. Among them, the compliance rate was53.3%in serum calcium levels; phosphorus level compliance rate was28.3%; phosphorus product Dada standard rate40.8%; iPTH level compliance rate of27.5%.5,25hydroxy vitamin D levels in patients with120cases in this study was28.12±13.60nmol/L, of which89cases (74.2%) patients with active vitamin D deficiency.6, mere are non-phosphorus product BSS group, mild and severe BSS group BSS group statistical differences in each group (p<0.05), but between serum calcium, phosphorus and iPTH groups was not statistically difference ((p>0.05).7, MHD presence of calcium and phosphorus metabolism in patients with abnormal calcium and phosphorus metabolism in their blood stasis score than patients with normal high (35.56±11.44vs.18.78±6.23, p<0.05).8, Multiple logistic regression analysis applied to conclude that age, systolic blood pressure, LDL-C, calcium-phosphorus product, serum albumin is a risk factor for the occurrence of blood stasis MHD (the combination of p values and confidence intervals).Conclusion:1, most of the patients undergoing maintenance hemodialysis presence of blood stasis, calcium and phosphorus metabolism,25(OH) D deficiency; medicine and certificates to QDBS common; calcium and phosphorus metabolism mainly as phosphorus-metabolism, calcium-phosphorus product, parathyroid hormone increased.2, MHD presence of calcium and phosphorus metabolism in patients with blood stasis syndrome score-significantly higher;5, senior citizens and systolic blood pressure, LDL-C, calcium-phosphate product increases, low serum albumin is an important risk factor for the occurrence of MHD patients with blood stasis;4, may exist between calcium and phosphorus metabolism and blood stasis syndrome causal relationship between the two.