Objective: Through clinical research, evaluation of XiaoZheng tablets in thetreatment of qi stagnation and blood stasis type of uterine myoma curative effect andclinical safety. And to discuss its mechanism of action, provide a basis to clinicalapplication. Methods: Clinical observation of65cases of uterine fibroids were randomlydivided into two groups, the treatment group of35cases of XiaoZheng tablets, cassiatuckahoe capsule30cases in the control group. Before and after treatment, symptoms andsigns to improve the situation, endocrine estrogen, progesterone changes, blood rheologylevel change and medication side effects. Results: XiaoZheng tablets on patients withuterine fibroids have better curative effect, the total effective rate was91.43%, with cassiatuckahoe capsule group (70%), there were significant differences (P <0.05), the treatmentgroup was superior to control group; syndrome of traditional Chinese medicine curativeeffect the total efficiency of85.71%, compared with the control group63.88%, differencesthere was significant (P <0.05), the treatment group was superior to control group. Inreducing uterine fibroid volume and uterine volume, compared with before treatment, thetreatment group had significant difference (P <0.05), comparison between groups hadsignificant difference (P <0.05). In the reduction of serum sex hormones in E2, P,compared with before treatment, group had significant difference (P <0.05),the differencebetween groups was significant (P <0.05). In the improvement of blood rheology level,compared with before treatment group had significant difference (P <0.01). Conclusion:XiaoZheng tablets in the treatment of qi stagnation and blood stasis type of uterine fibroidscan effectively improve clinical symptoms, reduce the size of uterine fibroids, improvepatients with endocrine and blood rheology level. The drug is safe and reliable, it is worthyof further. |