The Clinical Observation And Mechanism On Bronchial Asthma Of Wind-phlegm Syndrome Cured By San Ao Liu Jun Jian

Objective: To observe and evaluate the safety and efficacy of bronchial asthma ofwind-phlegm syndrome cured by San Ao Liu Jun Jian, and investigate the mechaniam.Methods: Based on the diagnostic criteria of bronchial asthma and Asthma disease ofwind-phlegm syndrome from 《Guidelines for the prevention and treatment of bronchialasthma》 and 《Guidance principle of clinical study on new drug of TCM about Asthmadisease》,60cases of bronchial asthma patients were distributed into two groups, the testgroup and the control group,30patients in each group. The test group were cured by SanAo Liu Jun Jian, and the control group by seretide. All of them were not givenglucocorticoid and have signed informed consent. Collect blood samples, measure theclinical symptom score, the maximum peak expiratory flow value, and the asthma controltest (ACT) score before treatments. Two groups were treated for1month. Observe changesof eosinophil chemotactic factor, clinical symptom score, asthma control test (ACT) scoreand Feng Liu mutation rate before and after the treatment and Evaluate the safety andefficacy.Results:1, peak flow meter to test the numerical comparison: the experimental groupand the control group after treatment before the peak flow meter test values were higherthan the treatment and control group peak flow meter test values were significantly lowerthan the experimental group (P <0.05), and there is statistically significant.2, eosinophilchemotactic factor comparison: the observation group was significantly lower chemokinesafter treatment eosinophils, there was a significant difference (P <0.05) than beforetreatment; controls eosinophil chemotactic factor after treatment after decreased, but therewas no significant difference (p>0.05) than before treatment.3, the clinical syndrome PTS: After treatment, there were significant differences (P <0.05) than before treatment, aftertreatment, the two groups, the experimental group than the control group, with statisticalsignificance (P <0.01).4, the Asthma Control Test (ACT) scores: after treatment thanbefore treatment scores were significantly different (P <0.01), scores between the twogroups, the experimental group than the control group, the difference was statisticallysignificant effect (P <0.05).Conclusion: San Ao Liu Jun Jian based on the conventional therapy can improve theclinical symptoms and signs and reduce the onset frequency on Asthma disease ofwind-phlegm syndrome. But all of them should be guided by the basic theory of traditionalChinese medicine. And the research have deepening the understanding of Asthma diseaseof wind-phlegm syndrome and optimized the modern treatment mode...