The Application Of Combining Conventional Ultrasound And Elastography In Diagnoses Thyroid Nodosity Disease

Objective:This study is to investigate the value of elastography and conventional ultrasound in differential diagnosis of benign and malignant thyroid nodules. The result is a great help for the choice of the surgery and clinical therapy.Methods:128thyroid nodules of80cases were checked by gray-scale ultrasound, color doppler ultrasound and elasticity imaging technique. All the nodules were confirmed by postoperative pathology. Observed the location, number, size, shape, border, capsule, internal echo, micro calcifications, internal and peripheral distribution of blood flow, peak systolic velocity (PSV), resistance index (RI) and elsatography score. Results:1. The gray-scale ultrasound image features of shape border, internal echo, coating and micro calcification between the benign and malignant thyroid nodules were significantly different (P<0.05). Diagnosis in the Alder grade, peak systolic velocity (PSV) and resistance index (RI) aspects the difference was statically significant (P<0.05). Diagnosis in the elastic classification the difference was statically significant (P <0.05).2.81thyroid benign nodules and47malignant thyroid nodules were diagnosed by conventional ultrasonic. The sensitivity of conventional ultrasonic diagnosis of thyroid nodules was71.8%(28/39), specificity was78.7%(70/89), and accuracy was76.6%(98/128).83thyroid benign nodules and45malignant thyroid nodules were diagnosed by ultrasonic elastogtraphy. The sensitivity of conventional ultrasonic diagnosis of thyroid nodules was69.2%(27/39), specificity was79.8%(71/89), and accuracy was76.6%(98/128).88thyroid benign nodules and40malignant thyroid nodules were diagnosed by conventional ultrasonic combined with ultrasonic elastogtraphy. The sensitivity of conventional ultrasonic diagnosis of thyroid nodules was89.7%(35/39), specificity was95.5%(85/89), and accuracy was93.8%(120/128).3. There was no significant difference between the sensitivity (χ2=0.06, P>0.05), specificity (χ2=0.03, P>0.05), and accuracy(χ2=0.00, P>0.05) of conventional ultrasonic and ultrasonic elastogtraphy. The sensitivity (χ2=4.04, P<0.05), specificity (χ2=10.1, P<0.05), and accuracy (χ2=15.0, P<0.05) of conventional ultrasonic were significantly lower than that of onventional ultrasonic combined with ultrasonic elastogtraphy. The sensitivity (χ2=5.03, P<0.05), specificity (χ2=10.2, P<0.05), and accuracy (χ2-15.0, P<0.05)of ultrasonic elastogtraphy were significantly lower than that of onventional ultrasonic combined with ultrasonic elastogtraphy. Conclusions:1. The diagnosis of thyroid nodules is based on gray-sacle ultrasound. Thyroid malignant nodules had more blood flow signals features and blood parameters in benign and malignant nodules. Therefore one cannot rely solely on indicators to be judged. It should be comprehensively analyzed when you want yo improve the accuracy of diagnosis.2. Ultrasound elasticity imaging can reflect the hardness of the organization. It provides more information for the diagnosis of benign and malignant thyroid nodules. Combination with conventional ultrasound greatly enhanced the accuracy of diagnosis. It has an important clinical value.