Clinical Value Of Gray-scale Ultrasound Combined With Superb Micro-vascular Imaging And Color Doppler Flow Imaging In Activity Evaluation For The Ulcerative Colitis

Objective: To explore the clinical value of gray-scale ultrasound combined with superb micro-vascular imaging(SMI)and color Doppler flow imaging(CDFI)in evaluating the activity of ulcerative colitis(UC),and to compare the evaluation results of two different blood flow imaging methods.Methods: Forty patients with ulcerative colitis in our hospital from January 2017 to January 2019 were collected and divided into active phase(n=26)and remission phase(n=14)according to the modified Mayo score.The differences of the measured values of gray-scale ultrasound(bowel wall thickness)between the two groups were comparatively analyzed.The bowel wall blood flow was measured by color Doppler imaging and superb micro-vascular imaging,respectively.The diagnostic effect of gray-scale ultrasound combined with superb micro-vascular imaging and color Doppler flow imaging on the activity of ulcerative colitis was estimated.Result: The thickness of bowel wall in active stage(5.6±1.4 mm)of ulcerative colitis was larger than that in remission stage(2.5±0.8 mm),the difference was statistically significant(P < 0.05).The distribution of blood flow signals in intestinal wall was examined by trans-abdominal ultrasound.The blood flow grading in UC active phase was higher than that in remission phase,and the difference was statistically significant(P < 0.05).The diagnostic accuracy of gray-scale ultrasound combined with CDFI and gray-scale ultrasound combined with SMI in UC patients was 72.5% and 90.0%,respectively.The intensity of gray-scale ultrasound combined with CDFI(Kappa coefficient was 0.474,P < 0.001)was moderately consistent with the improved Mayo score,and the intensity of gray-scale ultrasound combined with SMI(Kappa coefficient was 0.780,P < 0.001)was strongly consistent with the improved Mayo score.SMI is more consistent than CDFI(z was 2.28,P<0.05),the difference was statistically significant.Conclusion: There were significant differences in bowel wall thickness and blood flow distribution between remission and active UC patients.Gray-scale ultrasound combined with two blood flow imaging techniques had better effect in evaluating UC activity.Among them,the consistency of SMI and modified Mayo score was higher than CDFI,and the effect of evaluating UC activity was better.Therefore,gray-scale ultrasound combined with SMI is helpful to improve the accuracy of clinical evaluation of disease activity.