Clinical Effectiveness Research On Using Zheng Gusan Combined With Functional Exercise For The Treatment Of Knee Joint Osteoarthritis

Objective:To research the clinical effectiveness on using zheng gu san combined with clinical exercise for the treatment of osteoarthritis of the kneeMethod:60KOA patients were randomly divided into the treatment group and the control group.The treatment group patients received the treatment which included using zheng gu san combined with clinical exercise.The control group patients received the treatment which only included using zheng gu san.Two group patients had received the therapy for four weeks. Before and after the treatment,the muscle strength of flexion and extension of the knee, the JOA score, the VAS score, the thigh’s muscle volume and the range of motion of the knee were measured.Results:After the treatment,the JOA score of two group patients increased,the VAS score lowerd, the muscle strength of flexion and extension of the knee improved. There was significant difference(P<0.01) in these changes.The change of the treatment group improved more than the control group and there was statistical significance (P<0.05).Before and after the treatment,the thigh’s muscle volume of the treatment group had no change and there was no statistical difference (P>0.05).The thigh’s muscle volume of the control group decreased and there There was significant difference(P<0.01).Before and after the treatment, the thigh’s muscle volume of the control group decreased more than the treatment group and there was significant difference(P<0.01).It shows that the clinical exercise can prevent muscular atrophy. After the treatment,the range of motion of the knee of two group patients all increased and there was significant difference(P<0.01). But there was no significant difference (P>0.05) between the two groups in changes of the range of motion of the knee. Conclusion:KOA patients should early receive the treatment which is including using zheng gu san combined with clinical exercise.It can improve muscle strength and prevent muscular atrophy. The pain will be relieved. The range of motion of the knee will be increased and the function of the knee will be improved.