Relationship Between Personality Disorder Funetioning Styles And The Emotional States In Bipolar Ⅰand Ⅱ Disorders

Background:Bipolar disorder types Ⅰ (BD Ⅰ) and Ⅱ (BD Ⅱ) behave differently in clinical manifestations, normal personality traits, responses to pharmacotherapies, biochemical backgrounds and neuroimaging activations. How the varied emotional states of BD Ⅰ and Ⅱ are related to the comorbid personality disorders remains to be settled. Methods:We therefore administered the Plutchick-van Praag Depression Inventory (PVP), the Mood Disorder Questionnaire (MDQ), the Hypomanic Checklist-32(HCL-32), and the Parker Personality Measure (PERM) in37patients with BD Ⅰ,34BD Ⅱ, and in76healthy volunteers. Results:Compared to the healthy volunteers, patients with BD Ⅰ and Ⅱ scored higher on some PERM styles, PVP, MDQ and HCL-32scales. In BD I, the PERM Borderline style predicted the PVP scale; and Antisocial predicted HCL-32. In BD Ⅱ, Borderline, Dependant, Paranoid (-) and Schizoid (-) predicted PVP; Borderline predicted MDQ; Passive-Aggressive and Schizoid (-) predicted HCL-32. In controls, Borderline and Narcissistic (-) predicted PVP; Borderline and Dependant (-) predicted MDQ. Conclusion:Besides confirming the different predictability of the11functioning styles of personality disorder to BD I and Ⅱ, we found that the prediction was more common in BD Ⅱ, which might underlie its higher risk of suicide and poorer treatment outcome.