Clinical Analysis Of231Cases Of Serous Borderline Ovarian Tumor

OBJECTIVEThis study was undertaken retrospectively to discuss the characteristics of borderline ovary tumor (BOT), emphasized on serous BOT, and to explore the prognosis of fertility preserved treatment, as well as the risk factors of recurrence.MATERIALS AND METHODS:231medical records of patients, whose pathological results was confirmed as serous, a type of BOT, from January2004to December2013at Women’s Hospital School of Medicine Zhejiang University were analyzed. The clinical characteristics and pathological features of these patients were analysed.RESULTS:The average age of231patients was34.8years old (range from16to68).181patients were successfully followed,31patients suffered recurrence, however, none of them died during this period. The CA125level of these patients was between6.4IU/L and3835IU/L. Pelvic mass was the most common chief complaint. The patients in stage I were tend to adopt conserved surgical treatment. There was obvious statistic significance in the compassion of the incidence of SBOT at different age (P<0.05), as well as the recurrence of tumor with different clinical stage and the implantation of tumor in peritonaeum (P<0.05). Compared with radical surgery, the recurrent incidence of tumor in conserved surgery was much higher (P<0.05). Also, a relationship between recurrence and unilateral or bilateral, maximum tumor diameter and surgical manner was found in this study. Moreover, the recurrent incidence of tumor in patients with lymphnodes excision was lower than that of lymphnodes preserved(P<0.05), however, the survival rate was almost the same.Conclusions:SBOT often occurred in child-bearing women, fast frozen pathology of resected specimen during surgery was crucial for the diagnosis and the selection of surgical manner, and surgery was the main way to deal with SBOT. The recurrent incidence of SBOT with conserved surgery was higher than that with radical one. For young patients with fertility requirement at early stage, conservative operation was feasible, however, for patients without fertility desire, complete surgical staging should be given. Laparoscope surgery can be adopted when the diameter of tumor<5cm. After conserved surgery, the pregnancy rate of SBOT patients could still be satisfied. The major recurrent risk factors included FIGO stage, surgical manners, with or without peritonaeum implantation, unilateral or bilateral of tumor diameter, and surgical approaches, etc. The pathology of recurrent patients was almost the same, borderline tumor, and reoperation was feasible, also, the prognosis was good.