Macular And Peripapillary Retinal Nerve Fiber Layer Thickness With Hyperopic Anisometropic Amblyopia In Children

Purpose: To compare the foveal thickness and peripapillary retinal nerve fiber layer thickness in children with hyperopic anisometropic amblyopia, explore whether there is change of retinal structure with hyperopic anisometropic amblyopia.Methods: Take 43 patients(86 eyes) aged 4 to 7 with hyperopic anisometropic amblyopia in the He eye hospital Department of Ophthalmology September 2014-February 2015, measure the retinal nerve fiber layer thickness(including the foveal thickness and peripapillary retinal nerve fiber layer thickness),corrected visual acuity, ocular axial length and diopter.Results: Fovea retinal thickness increased in the amblyopic eyes compared with the fellow eyes,axial length and diopter increased in the amblyopic eyes compared with the fellow eyes,showing a statistically significant difference between them.However,no significant differences were found in the peripapillary retinal nerve fiber layer thickness between both eyes in the hyperopic anisometropic amblyopia(P=0.89).No correlation was found between the axial length and diopter with retinal nerve fiber layer thickness.Conclusions: There exists some difference in structure of macula between amblyopic eyes and non- amblyopic eyes in childen with unilateral hyperopic anisometropic amblyopia.