The Combined Risk Factors For Gastrointestinal Bleeding After Coronary Intervention Analysis

Objective Through the analysis of the patients’ clinical data with coronary heart disease in the First Affiliated Hospital of Kunming Medical University who were undergone percutaneous coronary intervention therapy (percutaneous transluminal coronary intervention, PCI) and had hemorrhage of gastrointestinal bleeding, GH), to evaluate the hemorrhage occurred rate, influence factors and outcome after percutaneous coronary intervention (PCI). The patients with hemorrhage in hospital investigated the treatment strategies to improved the level of treatment and the prognosis.Methods By retrospective case analysis,121 patients (male:94, female:27) with coronary heart disease, had treated with PCI, were selected from the Department of Cardiology of the First Affiliated Hospital of Kunming Medical University from August 2004 to November 2014. All of the patients,50 were gastrointestinal bleeding, 71 were no gastrointestinal bleeding. We recoded the general information of patients in detail. According to patients whether had gastrointestinal bleeding or not, the patients were divided into two group, combined with gastrointestinal bleeding group and not combined with gastrointestinal bleeding group. Then we analyzed the incidence and clinical systems of the gastrointestinal bleeding of the patients with different clinical factors, explored the affective factors of gastrointestinal bleeding after PCI.Results 1.Compared clinical data in the gastrointestinal bleeding group with not bleeding group:the age and days of usage of anticoagulant played significant effect on gastrointestinal bleeding in quantitative data.2. Through single factor analysis showed that the use of anticoagulants, peptic ulcer disease, taking non steroidal anti-inflammatory drugs, drinking, taking dual antiplatelet drugs in qualitative data had a significant effect in gastrointestinal bleeding patients.3.Through multivariate analysis, those which had remarkable influence on gastrointestinal bleeding were age, history of peptic ulcer, usage of non-steroidal anti-inflammatory drugs and drinking. For homologous risk, the age is 1.075 (95% CI:1.027,1.125), history of peptic ulcer is 8.251 (95%CI:2.998,22.708), usage of non-steroidal is 4.515 (95% CI:1.329,15.336), and drinking is 3.206 (95% CI:1.15,8.941).Conclusion 1.Age, anticoagulants use days, peptic ulcer disease, taking non steroidal anti-inflammatory drugs, drinking, taking dual antiplatelet drugs had a significant effect in gastrointestinal bleeding after PCI (P< 0.05).2. Age, history of peptic ulcer, taking non-steroidal anti-inflammatory drug, alcohol is an independent risk factor for gastrointestinal bleeding after PCI, respectively, from high to low risk of peptic ulcer history, taking non-steroidal anti-inflammatory drugs, alcohol age.