Study On The Mechanical And Biological Properties Of Electrospinning Biomineralized PCL/SF Blended Film

[Objective] In this study,the PCL/SF blended film with ideal thickness were manufactured by the self-designed metal collectors combined electrospinning,then the the membranes were detected after cross-linking and mineralization.[Methods]At first, solution with the ratio of PCL/SF at 3/7 was used to electrospin and gathered with the self-designed net collectors. Then the membranes were detected by scanning electron microscope and energy dispersive X-ray analysis. After cross-linking and mineralization, the mechanical properties^ antibacterial properties and the degradation performance in vitro of the blended membranes were tested and compared with collagen membranes.[Results](1) The sub-micron fiber films were made with the following parameters:20Kv voltage,12cm gap distance,2ml/h feed rate.10% PCL/SF solution was used and the smooth fiber with suitable diameter were obtained.(2) The self-designed net collectors compared with the traditional plate collectors were more likely to obtain the membranes with ideal thickness.(3) The mechanical properties were promoted after cross-linking; Alternative soaking solutions would gain the calcium and phosphorus on the membranes.(4) The tension test results of mineralized membranes and collagen menbranes were similar.(5) The degradation rate of mineralized membranes was slower than collagen membranes.(6) The mineralized membranes and collagen membranes had no forceful antibacterial properties.[Conclusion] In this study, the membranes with ideal thickness was obtained by self-designed collectors. After the post-processing, the physicochemical and biological properties of mineralized membranes was estimated compared with collagen membranes. The results revealed that the mineralized blended films exhibit good potential for engineering application.