| Objective: In this study, the left hind limb extension position fixed KOA rabbit model was established, using the Acupotomology as a whole lysis intervention, and with the widespread clinical use of knee articular injection of sodium hyaluronate control behavior observed in rabbit knee, knee passive activity, tibial and patellar ligament stretching angle, change the biomechanical properties of creep, stress relaxation, etc., from a biomechanical point of view to explore Acupotomy treatment KOA mechanism of action, for the treatment of this disease Acupotomy provided experimental basis.Methods: The 40 months of age 4 to 6 healthy male general level Japanese white rabbits, according to a randomized, controlled, balanced principle divided into: control group, model group, sodium hyaluronate group and acupuncture therapy groups 10 each. KOA established model, combined with the results of radiological assessment and behavioral observation in animal models using the left hind limb extension position fixation. Acupotomology Acupotomology treatment group overall lysis intervention control group using sodium hyaluronate knee articular injection of sodium hyaluronate, preclude the use of the knee joint assessment Lequesne MG rabbit behavior of each group were evaluated after calculating the total score. Measuring the degree of passive knee tibiofemoral angle, and compare the results of each group. Through the knee patellar ligament is stretched, the mechanical stress relaxation and creep tests to study the effects of Acupotomology lysis overall biomechanical properties of the patellar tendon.Resulets: 1. Behavioral results Before the intervention, the model group, sodium hyaluronate group and acupuncture therapy group Lequesne MG knee score was significantly increased compared with the control group, the statistical analysis, the difference was significant(P <0.01); after the intervention, sodium hyaluronate in the control group and the treatment group Acupotomology knee Lequesne MG scores decreased, which acupuncture therapy group, the most significant decline, acupuncture therapy group compared with model group there was a significant difference(P <0.01), sodium hyaluronate There was no control group and the control group significant difference(P> 0.05). Acupotomology treatment group and the control group sodium hyaluronate, there are significant differences between the two(P <0.05), and acupuncture therapy group Lequesne MG score below the knee of sodium hyaluronate in the control group.2. The results of the passive knee tibial angle measurement Model group and tibiofemoral joint activity angle were reduced compared with the control group, there was a significant difference(P <0.01); after the intervention, in the motion, sodium hyaluronate group treated with Acupotomology significantly increased, which increases the most obvious acupuncture therapy group, compared with model group acupuncture therapy there was a significant difference(P <0.01), sodium hyaluronate group and model group there was a significant difference(P <0.05). Acupotomology treatment group and the control group sodium hyaluronate, there was no significant difference(P> 0.05), but the knee acupuncture therapy group was significantly greater than the passive activity of sodium hyaluronate in the control group. On the tibiofemoral angle, sodium hyaluronate group and acupuncture therapy group was significantly increased, which increases the most obvious acupuncture therapy group, compared with model group acupuncture therapy there was a significant difference(P <0.01), hyaluronic acid there was a significant difference(P <0.05) of sodium in the control group and model group. Acupotomology treatment group and the control group sodium hyaluronate, there are significant differences between the two(P <0.05), and acupuncture therapy group was significantly greater than the knee passive activity of sodium hyaluronate in the control group.3. Knee patellar ligament creep and stress relaxation tests test results Model group, the patellar ligament "creep rate" and "stress relaxation rate" significantly reduced compared with the control group, there was a significant difference(P <0.01). After the intervention, the "creep rate", the Sodium hyaluronate group therapy group was significantly lower with the Acupotomology, which Acupotomology treatment group reduced the most obvious,Acupotomology treatment compared with model group had a significant difference(P <0.05), no significant difference(P sodium hyaluronate group and model group> 0.05). Acupotomology treatment group and the control group sodium hyaluronate, there are significant differences between the two(P <0.05). After the intervention, the stress relaxation rate, sodium hyaluronate control group and the treatment group was significantly lower Acupotomology, which reduces most obvious acupuncture therapy group, compared with model group acupuncture therapy there was a significant difference(P <0.01), glass there was a significant difference(P <0.05) of sodium in the control group and model group. Acupotomology treatment group and the control group sodium hyaluronate, there are significant differences between the two(P <0.05).4. Knee patellar tendon tensile test test results Model group, the maximum stress and maximum displacement reduced compared with the control group, there was a significant difference(P <0.01); the model group, the maximum displacement of decline, compared with the control group, there was a significant difference(P <0.01). After the intervention, the maximum stress, sodium hyaluronate Acupotomology treatment group and the control group was significantly increased, which increases the most obvious acupuncture therapy group, compared with model group acupuncture therapy there was a significant difference(P <0.01), There was no significant difference(P> 0.05) of sodium hyaluronate in the control group and model group. Acupotomology treatment group and the control group sodium hyaluronate, there are significant differences between the two(P <0.05), and the maximum stress acupuncture therapy group was significantly greater than in the control group sodium hyaluronate. After the intervention, the maximum displacement, sodium hyaluronate Acupotomology treatment group and the control group was significantly increased, which increases the most obvious acupuncture therapy group, compared with model group acupuncture therapy there was a significant difference(P <0.01), there was a significant difference(P <0.05) of sodium hyaluronate in the control group and model group. Acupotomology treatment group and the control group sodium hyaluronate, there was no significant difference(P> 0.05), but greater than the maximum displacement of acupuncture therapy group sodium hyaluronate group. After the intervention, the maximum strain, sodium hyaluronate Acupotomology treatment group and the control group was significantly reduced, which decreases acupuncture therapy group most obvious comparison there was a significant difference(P <0.01) with the model group acupuncture therapy, there was a significant difference(P <0.05) of sodium hyaluronate in the control group and model group. Acupotomy treatment group and the control group sodium hyaluronate, there are significant differences between the two(P <0.05), and acupuncture therapy group was significantly greater than the maximum strain of sodium hyaluronate in the control group.Conclusion: 1. whole Acupotomy lysis can significantly improve knee passive activity and tibiofemoral angle, ease tensions knee soft tissue contracture state regulation of stress and tension balance of the knee.2. whole Acupotomy lysis can significantly improve knee patellar tendon stretch, biomechanical properties of creep and stress relaxation mechanism may be adjusted within the joint Knife overall release tensile stress, balance of tensile stress and compressive stress, so that the knee reconstruction biomechanical balance, change abnormal stress on the patellar tendon stretch, so that the biomechanical properties of the patellar tendon is restored. |
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