Clinical Research On Nutcracker Phenomenon Combined With Or Without Glomerulonephritis In Proteinuria And Hematuresis Patients

Objective:To study the clinical features, laboratory examination and )ther factors to find the differences between simple nutcracker syndrome and nutcracker merge glomerulonephritis in proteinuria and hematuresis )atients, to improve the provides the reference for the clinical diagnosis of liseases, to provide evidence for clinical diagnosis of the disease,and to and the relationship between nutcracker syndrome and kidney disease by analysing the renal pathology of patient in nutcracker merge kidney disease.Methods:Between January 2010 and January 2015,90 patients who were outpatients/inpatients of the Department of Nephrology and Pediatric at Henan college of Traditional Chinese Medicine the first affiliated hospital With the clinical manifestations of left renal vein blood syndrome )atients for hematuria with proteinuria were enrolled.45 patients with simple left renal vein blood syndrome as the first division,the other 45 )atients with left renal vein blood syndrome combined with glomerulonephritis as the second division.General information age, gender, calculating body mass index, laboratory tests before and after exercise letermination of urinary red blood cell count, urinary red cell morphology, movement before and after 24h urine protein qualitative and quantitative urine protein, blood albuminwere observed of two groups,and carried on the analysis comparison. observed the pathological characteristics of nutcracker combined glomerulonephritis patients were collected.Results:Two groups of patients in age, sex, body mass index distribution had no significant differences (all were P>0.05), and from two groups patients in age composition than are in the majority with 14-29 years, )ody mass index distribution form on at a lower body mass index for the majority.Differences between two groups of patients with laboratory test results, after have statistical significance test, two groups of patients before and after exercise urinary red cell morphology, before and after exercise urine red blood cell count,24 H urine protein quantitative, plasma albumin was a significant difference (all were P<0.05).Students’sports before urinary red cell morphology homogeneity, non uniformity and mixed three, urinary red cell morphology after motion is non uniformity and mixed, and group b before and after exercise urinary red cell morphology was not changed, is still characterized by uniformity;Urine red blood cell count were higher than in group b before and after the students’movement, and two groups of patients with urine red blood cell count after exercise than before exercise increased obviously, first division in red blood cell count b change significantly;Students’quantitative level higher than group b,24 h urine protein and serum albumin in reducing b.Nutcracker merger glomerulonephritis patients with renal biopsy showed visible to a variety of )athological types:Kidney disease is minimal change disease 7 cases,5 sases with focal hyperplasia of sclerosing glomerulonephritis, membranous nephropathy in 11 cases,7 cases of mesangial proliferative kidney disease, IgA nephropathy 12 cases, appeared a variety of immune complex:IgA positive 17 cases,12 cases IgM and IgG positive 18 cases, C3 positive 15 cases, C4 positive in 1 case, Clq positive in 2 cases.Conclusion:(1)The left renal vein blood syndrome can merge glomerular nephritis;(2) The left renal vein blood syndrome, abnormal urine after motion and the biochemical indices abnormal, renal biopsy were suggested;(3)The nutcracker merger glomerulonephritis patients with pathologicalfindingsarediversity.