Echocardiography Tissue Doppler Techniques In Examining Systolic Functions Of Right Ventricular In Silicosis Patients With Cor Pulmonale

Objective: To discuss the early diagnostic value of echocardiography tissue Doppler techniques in detecting systolic functions of right ventricular walls in silicosis patients with cor pulmonale.Methods: 30 patients with pneumoconiosis complicated by cor pulmonale during January 2014 to January 2015(cor pulmonale group) were enrolled, whcih were in line with the diagnostic criteria of cor pulmonale; at the same time, 30 simple silicosis patients were enrolled as the control group. Except those with cor pulmonale, all patients above meet the diagnostic criteria of GBZ 70. 2002 Diagnostic Criteria of Pnemoconioses. Then some parameters of patients in both groups were measured respectively. The first kind of parameters included curves of tissue velocity imaging, tissue tracking imaging, tissue synchronization imaging, strain rate imaging and strain imaging in the subendocardial myocardium of the apex-mid-basis segment of the right ventricular inferior, anterior and lateral walls. The second kind of parameters included the time-to-peak velocity(TTPV),peak systolic displacement(PDs), average peak systolic velocity(APVs),, peak systolic strain rate(PSRs)peak systolic strain(PSs). At last, the correlation between every systolic parameter of each segment of right ventricular walls and the right ventricular ejection fraction(RVEF) in silicosis patients with cor pulmonale was analyzed.Results: In silicosis patients with cor pulmonale patients, the mean PSs in all segments of right ventricular walls, the mean PDs in basal segments of anterior, inferior, lateral walls and in mid segments of anterior walls, the mean PSRs in basal and mid segments of anterior walls and in mid segment of inferior walls, the mean TTPV in apical segment of lateral walls were all less than those in silicosis subjects(P<0.05) which was significant through the statistical analysis.Among all correlation analyses, PSRs in basal segment of anterior wall and mid segment of lateral wall, PSs in basal segment of anterior wall, PDs in basal segment of inferior and anterior walls were highly correlated with the measurements of RVEF; the diagnostic value of PSs in basal segment of inferior wall was larger; however, in silicosis patients with cor pulmonale patients,there was no linear correlation between the mean APVs, TTPv in all segments of right ventricular walls and RVEF(P>0.05).Conclusion: The systolic functions of right ventricular walls in the silicosis patients with cor pulmonale can be estimated by echocardiography tissue doppler techniques, particularly by strain imaging. And the regional myocardial systolic functions can be indirectly reflected by the measured value of tissue doppler parameters, which provides a noninvasive and effective examination method for the silicosis patients with cor pulmonale.