The Effect Of Compound Denshen Dripping Pills On The Patients’ Diameter Of Coronary Artery With Angina Pectoris Of QI Stagnation And Blood Stasis

Object:To investigate Compound Denshen Dripping pills’ effect and the mechanism on the diameter of coronary artery with Angina Pectoris of QI stagnation and blood stasis.Methods:Selected hospitalized patients with angina pectoris of QI stagnation and blood stasis from November 2014 to March 2015, with coronary angiography showed one (or more) Stricture of the coronary vessel diameter. Altogether collected 60 cases were randomly divided into research and control groups,30 cases of patients in each group. Two groups’ general information (age, gender, etc.) has no significant difference by X2 test. In the process of coronary angiography, each patient of the experimental group was given sublingual Compound Denshen Dripping pills and other patients of the control group was given sublingual nitroglycerin tablets, then Quantitative Coronary Analysis (QCA) is used to calculate the diameters and areas of the cornory areries of both groups.Results:(1) In the experimental group,the minimum lumen diameter (MLD),minimum lumen area(MLA),MLD%,MLA% of target lesion after sublingual Compound Denshen dripping pills 5min were significantly higher than which before sublingual pills (P<0.05); (2) In the control group after sublingual nitroglycerin tablets 5min, MLD,MLA,MLD% and MLA% had significant changes (P<0.05); (3) To compare two sets of datas, there is difference between the change before and after sublingual nitroglycerin or CDSD of MLD,MLA,MLD%, MLA%, but there was no statistical significance (P>0.05).Conclusion:Compound Danshen Dripping Pills and nitroglycerin are able to expand coronary artery diameter of coronary arteries. No significant difference of the degree between the expansion of coronary artery diameter were observed. Compound Danshen Dripping Pills can be used to treat patients with angina pectoris effectivly.