The Clinical Research Of Qingjin Sanjie Fang Combined With PP Scheme In Treating Patients Of Stage Ⅲ、Ⅳ Lung Adenocarcinoma

Object:Randomized controlled clinical study to observe clinical efficacy of Qingjin Sanjie fang combined with PP Scheme in treating patients of Stage Ⅲ、Ⅳ lung adenocarcinoma. From the recent objective response in patients with common clinical symptoms, physical condition, quality of life, of tumor marker levels, TK1, chemotherapy toxicity and other aspects of a comprehensive、real objective assessment of the clinical efficacy Qingjin sanjie treatment of lung cancer, provide the basis for clinical applications to further demonstrate the Chinese medicine treatment of pulmonary gland cancer characteristics and advantages.Methods:Using a randomized controlled method,60 definite patients with stage Ⅲ、Ⅳ lung adenocarcinoma have been assigned into two groups.30 in the test group (Qingjin Sanjie fang combined with PP Scheme),30 in the control group (chemotherapy with PP scheme only).21 days is a treatment cycle. After three cycles of treatment, clinical efficacy were observed between the two groups before and after treatment in patients with lung adenocarcinoma.Results:After treatment, the test group displayed more effective on controlling tumor growth, improving clinical symptoms, reducing the level of tumor markers (CEA、CA125、 CA199、CY21-1), enhancing the physical strength and the quality of life, reducing TK1 and the side effects of chemotherapy. Showing significant difference between the two groups (P<0.05). But after treatment, comparing the cancer short-term objective efficacy in two groups of patients, efficiency were 33.33% and 30.00%, there was no significant difference between the two groups (P>0.05)Conclusion:Compared with chemotherapy alone, Qingjin Sanjie fang combined with PP Scheme in treating patients of Stage Ⅲ、Ⅳ lung adenocarcinoma can effectively improve clinical symptoms, enhance the physical strength and QOL of patients, reduce the level of tumor markers, inhibit tumor cell proliferation, lower tumor burden, and reduce the side effects of chemotherapy, which is worthy of clinical application and promotion.