| Objectives To investigate the feasibility and clinical singificance of intercostobrachial nerve reservation in breast cancer surgery operation.Methods Clinical follow-up: the North China University of Science and Technology and Langfang People’s Hospitaloncology in July 2004 to July 2009, clinical data of patients with breast cancer operation, a total of 370 cases. Among them, the group for the Preserva tion of the intercostobrachial nerve group, 101 cases; another group was resected intercostobrachial nerve group, 269 cases. During the research: comparison of two groups of patients with operation time,intraoperative blood loss and the number of lymph node dissection differences; variations were analyzed between two groups of patients who were postoperative 1week, 1 month and 6 months with sensory dysfunction and motor dysfunction rate differences;incidences were analyzed between two groups of patients with local recurrence, distant metastasis after 5 years postoperative and survival.Results Compared two groups of patients with operation time, intraoperative blood loss, number of lymph node dissection, and the difference was not statistically significant( t=-2.13,P=0.34;t=2.06,P=0.40;t=-1.30, P=0.19); Postoperative 1 week,1 month, 6 months of preservation of intercostobrachial nerve group and resection group the incidence of sensory disturbance were 69.31%, 80.67%, 34.65%, 48.70%, 16.83% and 28.62%, the differences were statistically significant(χ2=5.45, P=0.02; χ2=5.86, P=0.02; χ2=5.39, P=0.02);Patients with postoperative 1 month and 6 months of preservation of inter costobrachial nerve dysfunction group and resection group were 23.76%,36.80%,16.83%, 29.74%, the difference was statistically significant(χ2=5.63,P=0.02;χ2=6.33,P=0.01); The incidence rate and 5 year survival rate of patients with metastasis 5 years after the operation of preserving intercostobrachial nerve group and local recurrence, distant resection group, the difference was not statistically significant(χ2=6.38,P=0.12;χ2=0.54,P=0.46;χ2=0.25,P=0.61).Conclusions 1 Preserve intercostobrachial nerve dose not prolong the total surgery time significantly, not increase the amount of blood bleeding during the operation, not prevent the thorough cleaning of the Axillary Lymph Node Dissection and dose not increase the risks of axillary recurrence and metastasis.2 Preservation of intercostobrachial nerve can decrease the incidence of sensory disturbance in upper arm and axillary,and improve the quality of life. |
