Narrow-band Imaging Magnifying Endoscopy Can Optimize The Diagnosis Of Chronic Atrophic Gastritis

Objective:To investigate the clinical value by using narrow-banding imaging magnifying endoscopy for diagnosis gastric atrophy, intestinal metaplasia and intraepithelial neoplasia.The NBI-ME after C-WLI inspection checks is an ideal checking strategy.Methods:The subjects selected 200 patients who came fromthe endoscopy room of the First Hospital of Shanxi Medical university in 2013, December-2014,December.Those patients were randomly divided into two groups: conventionall endoscopic observation group(n=100), the NBI-ME observation group(n=100). C-WLI group only uses C-WLI observation,and NBI-ME group were observed the stragy after C-WLI Joint NBI-ME observations. Two groups of patients were taken after endoscopy pathology tests to pathology as the gold standard, and analysis the endoscopic findings and pathology results.Clinical diagnosis test uses fourfold table method with pathology as the gold standard, the endoscopic findings and pathology results of comparative analysis to calculate the sensitivity, specificity, positive predictive value, negative predictive value,Youden index, which evaluate the clinical value of the Joint Inspection methods.Results:1、For the atrophic gastritis diagnose the C-WLI group is a sensitivity was 49.48%, a specificity of 59.45%; the NBI-ME groups is a sensitivity of 89.66%, a specificity of63.33%.2、For the intestinal metaplasia lesions diagnose,the C-WLI group is a sensitivity of44.45%, a specificity of 64.19%; NBI-ME group is a sensitivity of 89.36%, a specificity of89.33%.3、For intraepithelial neoplasia diagnose the C-WLI group is a sensitivity of 48.48%and a specificity of 61.53%, NBI-ME group is a sensitivity of 84.21%, a specificity of95.93%.4、NBI-ME group applyes the strategy of NBI-ME after C-WLI observetion, observing intestinal metaplasia, Intraepithelial neoplasia of diagnosis, is better to reflect its superiority.Conclusions:NBI-ME after C-WLI can significantly improve the chronic atrophic gastritis,intestinal metaplasia and intraepithelial neoplasia diagnostic accuracy, and can effectively guide targeted biopsies, and can be used as a follow-up examination Method for CAG.