| Objective:To evaluate the application of artificial vertebra of n-HA/PA66 in anterior reconstruction of lower cervical spine fracture and dislocation.Methods:In this retrospective study, a total 50 patients with lower cervical spine fracture and dislocation received anterior cervical corpectomy and fusion. The patients were divided into two groups according to the material of reconstruction used (TMC or n-HA/PA66 artificial vertebral body). Clinical and radiological parameters were used to evaluate outcomes.Results:All the patients underwent operation successfully and there were 43 patients followed up for 6 to 24 months. The preoperative symptoms were improved to varying degrees. Imaging study showed that the vertebral height and Cobb angle compared with the preoperative had statistical significance (P<0.05); at 3 months follow-up the loss of vertebral height in artificial vertebral body group were (0.57±1.33) mm, which were significantly less than the titanium mesh group (2.57±2.21) mm, the difference was statistically significant (T=3.140, P=0.006); at the final follow-up difference were further increased.Conclusion:As the material of reconstruction, nano-hydroxyapatite/polyamide 66 (n-HA/PA-66) composite artificial vertebral body, it could reconstructive the cervical stability, effectively restore vertebral height, reduce vertebral sedimentation occurs, but the long-term effect needs further observation. |
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