| Objective:To analyze the changes of corneal endothelium after repeatedly Retinal laser photocoagulation.Methods:This was a nonrandomized clinical study, fifty-five pat ients 55 eyes (pick right one) who underwent panrentinal photocoagul ation were recruited. The cornea was divided into 3 sections s includ ing central,12 point,6 point. The Corneal endothelial meter was use d to collect CECs’ patameter data. The data analysis were done separ ately by the variance analysis and Least-significant difference.Results:Comparing the data before and 28 days after in 3 secti ons, there were significant difference (both P<0.05) in the Hexagona 1 cell percentage(HEX) (12 point changed from 65.09±18.60% to 63. 39±18.39%, F=1.679;6 point changed from 64.86±18.48% to 62.95±1 7.66%,F=1.978). And there were significant difference (all P<0.05) in the Coefficient of Variation (CV) (cornea from 26.24±3.99% to 27. 00±4.48%, F=4.122;12 point from 26.19±4.09% to 27.14±4.47%, F=4. 183;6 point from 26.17±4.34% to 27.38±4.18%, F=4.079. Moreover, t here were significant difference (all P<0.05) in the average cell area (AVE) (cornea from 387.81±49.92μm2 to 404.48±50.59μm2, F=5.136; 12 point from 385.71±46.91μ2 to 408.38±53.70μm2, F=5.566; 6 poi nt from 388.85±46.02μm2 to 406.04±50.71μm2, F=6.894). However, t he cell density(CD) was not statistically significant among 3 sections (all P>0.05). Conclusion:ECEs were changed in a short time after the repeatedly treatment of Retinal laser photocoagulation, especial the Hexagon al cell percentage and the average cell area, it’s highly related to lase r energy. |
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