Research On Correlation Between TCM Syndromes Of UC And Constitution And Anxiety, Depression

Objective:In this study, by collecting the clinical data of 80 cases of patients with ulcerative colitis(UC), respectively on the TCM syndrome type, constitution, anxiety and depression were determined, a preliminary analysis of the correlation between TCM syndrome types of UC and constitution and anxiety, depression, to provide a reference and basis for the treatment of UC prevention and clinical.Methods:This study using clinical epidemiological questionnaire survey method, by reference to the UC with integrated traditional Chinese and Western medicine combined with diagnosis and treatment plan prepared " UC clinical information questionnaire " and combined with the clinician’s experience in syndrome differentiation in patients with TCM syndrome type were determined, the reference to " Chinese constitution classification and decision table " to the patient’s constitution determine the type of,SAS and SDS were used to determine whether the patients had anxiety and depression. Data will be collected by finishing and to deal with statistical analysis and preliminary study on the correlation between TCM syndrome types of UC and constitution and anxiety, depression..Results:1. general information:(1) Male 42, female 38, male and female ratio is 1.105:1. The incidence of young group was the highest(53.75%). There is no association between age and gender in the onset of UC(P>0.05).(2) The patients had the highest, 60% of the patients with hypertension, and the highest in past history, accounting for 20%.(3) Diet not partial addicted person most(37.50%), biased addicted to the partial fat(22.5%), sweeter(13.75%), drinking(8.75%) and partial spicy(7.50%) more.(4) The clinical type of chronic recurrent hair was the highest(56.25%).(5) The lesions were the most common in rectum and rectum, and were 31.25% and 33.75% respectively.(6) The course of the disease and the severity of the disease significantly correlated(P < 0.01): mild most(53.75%). The duration of disease 1-5 years most(55.00%). The course of disease <1 and1-5 were mild, with moderate to 88.24% and 59.09%, 5-10 years in moderate to most(71.43%), >10 years were severe.(7) The active period(82.50%) was significantly morethan the remission period. And the active period of the youth group and middle age group, the remission period to the old group is more.2. The TCM syndrome type distribution: syndrome of dampness heat in large intestine most(31.25%), followed by the rest of syndrome of deficiency of spleen qi and stomach qi(27.5%), liver stagnation and spleen deficiency syndrome(15.00%), spleen kidney yang deficiency syndrome(12.50%), blood stasis intestine collaterals syndrome(8.75%) and Yinxue deficiency syndrome(5.00%).3. Constitution type distribution: Damp heat constitution most(23.75%), the rest of the followed by qi deficiency(17.50%), deficiency of Yang(15.00%), phlegm(11.25%),Qi Stagnation(11.25%), flat and quality(10.00%), blood stasis(7.50%), Yin deficiency(2.50%), special intrinsic quality(1.25%).4. The distribution of anxiety and depression: 55 cases of anxiety, depression, 72.50%,of which 32 cases of anxiety(44%), 26 cases of depression(32.50%).5. TCM syndrome type and type of constitution are significantly correlated(P < 0.01):Patients with syndrome of dampness heat in large intestine damp heat constitution most(60.00%), secondly phlegm dampness constitution(24.00%); syndrome of deficiency of spleen qi and stomach qi patients with Qi deficiency and yang deficiency are more,respectively, accounting for 36.36% and 27.27%; spleen kidney yang deficiency syndrome in Zhongyang virtual mass most(50.00%); patients with liver depression and spleen deficiency gas stagnation most(50.00%); Yin and blood deficiency patients Zhongping and quality, Qi deficiency, yin deficiency and intrinsic quality, accounting for 25.00%; intestine collateral blood stasis syndrome in patients with blood stasis most(42.86%), followed by hydrothermal matter(28.57%).6. TCM syndrome type with anxiety and depression have correlation(P<0.05): Liver stagnation and spleen deficiency syndrome patients with anxiety, the incidence of depression was 100%. Secondly, the deficiency of spleen and stomach qi deficiency syndrome(77.27%), heat dampness heat syndrome(68%) more. The anxiety of liver stagnation and spleen deficiency syndrome incidence was the highest(75.00%), secondly was large intestine wet heat syndrome(52.00%), deficiency of spleen and stomach qi depression incidence rate was the highest(59.09%), followed by liver stagnation and spleen deficiency syndrome(50.00%).7. Physical types were associated with anxiety and depression(P<0.05): The incidence of anxiety and depression in patients with qi depression was 100%. Secondly, Qi deficiency substance(92.86%), dampness heat(89.47%) and yang deficiency substance(66.67%) were also higher. The incidence of anxiety was the highest(77.78%) and the second was dampness heat(68.42%), and the incidence of depression was the highest(64.29%) and the second was Qi Stagnation(55.56%).8. The correlation between TCM syndrome type, constitution type, anxiety, depression and other factors:(1) There is a clear correlation between the syndromes of TCM and the severity of the disease(P<0.01): mild to large intestine damp heat syndrome most(44.19%), moderate in spleen and stomach qi deficiency syndrome most(26.67%), severe to stagnation and spleen deficiency syndrome mainly(71.43%).(2) There is a correlation between the physical severity and the severity of the disease(P<0.01): the most of the mild heat and dampness was the highest(34.88%), and the medium was Qi deficiency(26.67%),and severe to the Qi Stagnation(57.14%).(3) There is a correlation between the Constitution and the course of the disease(P<0.01): duration of < 1 year to dampness heat up(41.18%), 1-5 years to Qi deficiency and damp heat constitution based, each accounting for 27.27%, 5-10 years of qi stagnation mainly(42.86%), over 10 years of Yang quality based(60.00%).(4) there was no correlation between anxiety, depression and gender(P>0.05).(5) Anxiety, depression and the course of disease(P<0.05): course for a higher incidence of 1-5 years and 5-10 years of patients with anxiety and depression, respectively,accounting for 84.09% and 85.71% and the duration of the disease was 5-10 years of patients with anxiety(64.29%), depression(42.86%), the incidence was highest.(6)Anxiety and depression were associated with clinical types(P<0.05): the incidence of anxiety and depression in patients with chronic recurrent onset was the highest(86.67%).Conclusion:(1) There is a correlation between UC TCM syndrome and constitution type. The outcome of physique can influence the nature, syndrome type, and the type of syndrome in Conghua, have a certain guiding role. Master of the disease susceptible, utilize the physique of the tunability, of susceptible population in the early to take intervention measures, can prevent disease before, "governance not disease"; to have been ill can be taken, "identified on governance" and "treatment based on syndrome differentiationcombined treatment, the essence of a comprehensive understanding of the disease, to fundamentally prevent and treatment of this disease.(2) UC syndrome and anxiety and depression were related. Because the emotion in a certain extent, affects the generation and relapse of the disease, so in the clinical differentiation of symptoms and signs, for liver stagnation and spleen deficiency syndrome and syndrome of dampness heat in large intestine patients anxiety irritable, deficiency of spleen and liver stagnation and spleen deficiency syndrome in patients with depressive symptoms, strengthen for diet instruction and the emotion nursing, and with soothing the liver stagnation of Qi of traditional Chinese medicine, can effectively improve the clinical effect and improve the life quality of the patients.(3) UC constitution and anxiety and depression were related. The constitution is the intrinsic basis of emotional changes, and emotional change time will affect and change the constitution. Constitution can be tone, emotion as the important factor causing the disease,through the improvement and rectification of the biased constitution to regulate emotions and reduce risk; also can improve anxiety and depression, change susceptible constitution,is helpful to improve the cure rate and reduce the recurrence rate.