Performance Research Of Mn²⁺ Doped β-TCP Porous Bionic Bone Materials

Bone is an important part of human body, bone has the function of maintaining normal physiological function, resisting the external force, supporting the organ. In recent years,bone defects caused by traffic accident and disease bring a great distress for normal person on their production and living. Therefore, the development of bone substitution materials to meet the demand of human body function is of great significance. β-tricalcium phosphate is biological absorbable material, and its inorganic component is similar to bone,now β-TCP is the focus of current study because of its biocompatibility, biodegradability and so on. Manganese is one of important trace metal elements that are helpful for bone growth, manganese plays a significant role in the synthesis of chondroitin sulfate, and chondroitin sulfate is an important component for bone formation. Therefore, this paper carried out performance research of Mn²⁺ doped β-TCP porous bionic bone materials is of great significance.In this paper, using the sol-gel method by Ca+Mn/P=1.5 ratio synthesis of 5%、15%、30%Mn-doped β-TCP powders. The XRD analysis showed that Mn²⁺ doped β-TCP powder crystallinity was better, after Mn²⁺ replacing Ca2+ in the lattice, all the characteristic diffraction peaks moved to the high angle, and the spacing of lattice decreased. With the content of Mn²⁺ doping increased, the β-TCP lattice constant A decreasing. And C showed a trend of increasing then decreasing afterwards. Particle size analysis showed the size of Mn²⁺ doped β-TCP powder was small and distributed uniform, the size of most powders were under 40 microns.In the preparation of Mn²⁺ doped porous materials, through compression strength test selecting 6wt% PVA solution as binder, 30wt% stearic acid as pore-forming agent, so the porous materials performed well both in mechanical performance and porosity. With the content of Mn²⁺ doping increased, the porous materials volume shrinkage significantly.The SEM analysis showed that there existed three- dimensional porous structure with good pore connectivity in the interior of porous bionic bone materials, that was favorable for bone cell adhesion and bone ingrowth, to meet the requirement of bone imitation materials.Mn²⁺ doped β-TCP porous bionic bone materials were tested for degradation performance in 1.5SBF solution for 28 days. XRD and FTIR analysis showed that after degradation some bone-like apatite materials deposited on the surface of porous materials.With the content of Mn²⁺ doping increased, the amount of newly generated bone-like apatite materials decreased, however the crystallinity increased significantly. PH analysis showed that alkaline environment was conducive to deposit bone-like materials.Research on friction and wear properties of 0%Mn-TCP, 5%Mn-TCP, 15% Mn-TCP,30%Mn-TCP respectively in dry friction, SBF solution and plasma lubrication condition.With the content of Mn²⁺ doping increased, the steady friction coefficient of the sample increased obviously. It should be that the lattice structure shrinking caused by Mn²⁺ doped,increased the surface roughness. The steady friction coefficient of 0%Mn-TCP changed sharply in different lubrication condition, the maximum was 0.10 in condition of dry friction and the minimum was 0.06 in condition of SBF solution. However, the steady friction coefficient of 5%Mn-TCP, 15% Mn-TCP, 30%Mn-TCP changed in the same way,the maximum was under the lubrication condition of dry friction and the minimum was under the lubrication condition of plasma.