The Analysis Of CT Perfusion Imaging For Patients With Unilateral Internal Carotid Artery Occlusion

Perfusion is a narrow artery blood supply and collateral blood flow of the flow within the joint decision, in order to study the relationship between the collateral blood flow and brain tissue perfusion, we selected patients with unilateral carotid artery occlusion, the pathological changes of the hemisphere blood perfusion was the collateral vessels of supply,the current study is limited to the types of collateral, but more limited to qualitative research, such as shall be able to quantify and collateral blood flow perfusion index combined, will be more conducive to the understanding of the mechanism of the role of collateral and infarction.This study analysis DSA confirmed the existence of unilateral internal carotid artery stenosis in patients with head CT perfusion(CTP) were retrospectively analyzed using the method of semi-quantitative analysis of related parameters.Purpose:In patients with unilateral internal carotid artery occlusion for head CT perfusion, analysis of block collateral compensatory situation of side of the brain and cerebral blood flow dynamics.Methods:Choose on January 1, 2012 to October 31, 2015 in the fellowship at jilin university hospital neurology DSA demonstrated a unilateral internal carotid artery occlusion, the contralateral normal or narrow degree nomore than 30% and the head CT scan to rule out large area cerebral infarction, cerebral hemorrhage, intracranial tumor patients of cerebral CT perfusion, conform to the standards of a total of 22 people.According to former head DSA can be divided into traffic unclogged arteries open ACOA group of eight people, after the traffic artery PCOA group of four people and traffic artery before and after opening A and PCOA group of ten people choose the arteries in the brain cortex area, cortex watershed area before and after the cortex in watershed area and wear the area of the watershed area, A total of five areas,Finally obtain local cerebral blood flow(of regional cerebral blood flow, rCBF), regional cerebral blood volume(regional cereb ral blood volum, rCBV), average through time,mean transit time, determined by MTT) and the maximum peak time(the time to peak, TTP) parameters. According to the four values and the relationship between the hemodynamic parameters, to discuss collateral compensatory of unilateral internal carotid artery occlusion side of the brain and cerebral blood flow dynamics.Results:1. Patients with unilateral internal carotid artery occlusion bilateral four parameters in statistical rCBV no statistical significance, rCBF, TTP,determined by MTT have statistical significance.2. Simple traffic artery in patients with unilateral internal carotid artery occlusion and pure after traffic artery open TTP,determined by MTT has statistical significance. Before the unilateral internal carotid artery occlusion in patients with pure traffic artery and before and after the traffic artery open TTP, determined by MTT has statistical significance. In patients with unilateral internal carotid artery occlusion after simple traffic artery and before and after the traffic artery open rCBV, rCBF, TTP, determined by MTT have statistical significance.Conclusion:1.Patients with unilateral internal carotid artery occlusion on both sides of the brain hemodynamic abnormalities.2.Simple traffic artery in patients with unilateral internal carotid artery occlusion with simple traffic artery open after has better perfusion.Unilateral carotid artery occlusion in patients with pure traffic artery before than before and after the traffic arteries are less open perfusion.After unilateral internal carotid artery occlusion in patients with pure open traffic artery than before and after the traffic artery perfusion is poorer and more obvious.