| Malignant tumor has become the first killer of human health. In the process of fighting with cancer, many new methods have been invented and new theories have been created. Glioblastoma multiforme(GBM), skin melanoma and liver metastases, and boron neutron capture therapy (BNCT) is the only effective treatment. Neutron source for BNCT is not only to meet the needs of clinical treatment, but also to be suitable for use in hospital installation. So accelerator based boron neutron capture therapy (AB-BNCT) has attracted much attention. The United States, Japan, the European Union and other countries compete to carry out the relevant research AB-BNCT.For more neutron and less radio activity we used Monte Carlo method to simulate the reaction and we get the result that will be useful for develop neutron target.We develop a software using GEANT4.In order to verify the reliability of Monte Carlo simulation, this paper simulated the Li (p, n) Be reaction and compared the existing theoretical data. The program is suit for simulate these reactions. We simulate three kind reaction Li(p, n),Be(p, n)and Be(d, n), we contrast the three kinds of reaction. We get the result that under the thick target condition, the target’s reaction Li (p, n) Be product neutron field with the better energy spectrum when the incident proton is near the threshold, and the angular distribution is more suitable for the use of AB-BNCT.In this paper, the Monte Carlo algorithm are also studied theoretically applied to the particle transport process, and how to use Geant4 compiled simulation program. |