Research Of Association Between Orthostatic Blood Pressure And Arteriosclerosis In Elder People

Objective: The aim of this study was to discuss the relationship the change of orthostatic blood pressure and arteriosclerosis in elder people. Methods: Elder patient(age ≥ 80 years)who admitted to our ward of First Affiliated Hospital of Xinjiang Medical University Department from 2014.6 to 2015.12. A total 227 patients(male146,mean age 82.61±3.40 years; female 81, mean age 81.63±2.37 years) were enrolled in this study. Aaccording to the change of orthostatic blood, patient were divided into three groups: orthostatic normotension group,orthostatic hypotension group,orthostatic hypertension group,using Limb Doppler ultrasonography to assess pulse wave velocity and ankle brachial index. To compare the change of orthostatic blood pressure and arteriosclerosis in elder people. Results:(1) In this study OH prevalence was 22.50%and OHT prevalence was 11% in 227 elder people.(2) The comparision of age in ONT group and OHT group was statistically significant difference(ONT:82.32±3.15,OHT:83.93±2.99,t:-2.038 P <0.05); The comparision of Morse in ONT group and OH group was statistically significant difference(ONT49.37±17.25,OH57.40±17.92,t:-2.901P<0.05).(3)The comparision of diabetes in ONT group and OH group was statistically significant difference(2? =3.671,P<0.05).(4)The comparision of bilateral ABI in ONT group and OH group was statistically significant difference( P < 0.05). The comparision of low-ABI in ONT group and OH group was statistically significant difference(P<0.05).(5)The comparision of use five-class antihypertensive medication in ONT group and OH group was no statistically significant difference(P>0.05).(6)After multivariate logistic regression analysis,low-ABI was one of OH independent risk factor(OR 值:20.776,95% CI:7.449~57.947,P 值:0.000). Speculated that arteriosclerosis may be associated with the onset of OH.The OH risk increased by 1.035 times in population with high-Morse score compared those with normal-Morse score,these data provide no evidence for the association between the elder and blood-glucose in OH risk.(7)After multivariate logistic regression analysis,elder was one of OHT independent risk factor(OR 值:1.169,95% CI:1.014~1.348,P 值:0.031),these data provide no evidence for the association between the ABI 、Morse and blood-glucose in OHT risk. Conclusion:(1)The OH incidence in elder was22.5%,the OHT incidence in elder was 11%.(2)Low-ABI was one of OH independent risk factor in elder people,these data provide no evidence for the association with bapwv in the change of orthostatic blood pressure.(3)The elder was one of OHT independent risk factor,these data provide no evidence for the association with age in OH.(4) Morse score maybe predict the risk of OH independent.