Application Research Of PDCA Cycle Theory In Rational Administration Of Drug

Objective To investigate the rationality of prescription among outpatients and hospital doctor in our hospital to use rational use of drug of medical institutions, reference PDCA (Plan, Do, Check, Action) cycle (Deming cycle) theory, and applied to the application of rational administration of drug in medical institutions, to discover new ideas and find new solutions to promote the rational use of drugs.Methods As the research object to analyze the indicators of rational drug use among outpatients from December 2014 to December 2015, and the indicators of rational drug use of doctor’s orders from August 2014 to August 2015, and the indicators of rational drug use of doctor’s orders of clean surgical operation from September 2014 to September 2015, using the PASS of our hospital clinical pharmacy management system, random sampling method with fixed number of prescriptions which randomly selected as the pre-intervention and post-intervention of a certain number of outpatient and inpatient medical records from the hospital information system (HIS). using Microsoft Office Excel to collect patient sex, age, diagnosis, prescription and prescription doctor and to count the rational drug use indicators of medical institutions.using data statistical analysis software (Product and Service Solutions Statistical, SPSS IBM) to analysis and evaluate the effect of PDCA intervention on rational drug use in our hospital.Results We investigated 18000 outpatients’ prescriptions, the results showed that the average number of drug types of single prescription was dropped from 2.31 (pre-intervention) to 1.88 (post-intervention, P< 0.05); the use rate of antibacterial drugs was dropped significantly from 30.67%(pre-intervention) to 8.98%(post-intervention, P< 0.01); the use rate of injections was dropped significantly from 54.02%(pre-intervention) to 25.35% (post-intervention, P< 0.01); the use rate of basic drugs was risen significantly from 65.97% (pre-intervention) to 58.38%(post-intervention, P< 0.05); the average cost was dropped from 94.63 Yuan (pre-intervention) to 84.37 Yuan (post-intervention, P < 0.05)We investigated 1800 hospital doctors, the average number of antibacterial drugs types was dropped from 2.01 (pre-intervention) to 1.81 (post-intervention, P< 0.05); the average number of antibacterial drugs cost was dropped from 2397.83 Yuan (pre-intervention) to 954.27 Yuan (post-intervention, P< 0.01); the use rate of antibacterial drugs was dropped significantly from 66.17%(pre-intervention) to 30.17%(post-intervention, P< 0.01); the dose of antimicrobial drug [DDD/ (100person·day)] was dropped significantly from 42.14 (pre-intervention) to 33.33 (post-intervention, P< 0.01); the cost rate of antibacterial drugs was dropped significantly from 28.47%(pre-intervention) to 14.18%(post-intervention, P< 0.01); the use rate of special use level of antibacterial drugs was dropped significantly from 5.00%(pre-intervention) to 1.17%(post-intervention, P<0.01); pathogenic examination percentage of antibacterial drugs was risen from 52.78% (pre-intervention) to 69.02%(post-intervention, P< 0.05).We investigated 1800 doctor’s advice on the prevention of cleaning operation, the use rate of antibacterial drugs was dropped significantly from 45.83% (pre-intervention) to 26.83% (post-intervention, P< 0.01); per capita drug use days was dropped significantly from 2.63 (pre-intervention) to 2.33 (post-intervention); the percentage administration of the patients who received the 0.5-2.0 hours before cleaning operation was risen from 11.87%(pre-intervention) to 18.83% (post-intervention, P< 0.05).The percentage administration of the patients who received the 0.5-2.0 hours before hip replacement was risen from 55.93% (pre-intervention) to 100% (post-intervention, P< 0.01); the percentage administration of the patients who received the 0.5-2.0 hours before knee replacement was risen from 44.44% (pre-intervention) to 50.00%(post-intervention, P< 0.05); the percentage administration of the patients who received the 0.5-2.0 hours before hysteromyomectomy was risen from 0 (pre-intervention) to 30.55% (post-intervention, P< 0.05).Conclusions:This topic provides new ideas of thinking for application research of rational administration of drug, through the PDCA cycle theory in clinical application, which make the clinical medication more standardized, and provide baseline data of the present situation of rational drug use for medical management and health policy makers, and further improve the rational use of drugs and better implementation the medication policy of safe, effective and appropriate.