| ObjectiveHepatocecllular carcinoma(HCC) is one of the common malignant tumor of the earth, its the worst tumor of prognosis. Portion of the HCC found h ave been middle-late, lost the best opportunity to issue of surgical rese ction, for this kind of situation is the most commonly used Tran theter h epatic arterial chemoembolization (TACE)of HCC patients, is one of the me thods of local treatment. With percutaneous hepatic artery embolism chemot herapy surgery with conventional treatment of locally, is not a complete removal of the tumor cells,but only to stop the flow of blood to the tum or, the tumor is also in the local, Many revive and the surrounding portion of the tumor cells for angiogenesis maby. Impact on the quality of surviv al And after the intervention of adverse reactions. There are some advanta ges of TCM in the treatment of liver cancer. According to the rationale li ver Spleen "Golden Chamber", Through the method of Jianpi Huayu Decoction invigorating blood circulation of traditional Chinese medicine for HCC p atients after surgery with conventional clinical observation, The purpose of my study is To further explore the HCC patientsclinical effectiveness and safety after the TACE. To explore in the treatment of TCM. and the Fur ther treatment provides after TACE.MethodsThis topic is selected 80 HCC Patients according to the standard in to two groups according to the requirements, Two groups of patients use TA CE, The treatment group use the Jianpi Huayu Decoction and the Western med icine comprehensive treatment, the other grope only use the later. Were ob served before and after one month, there mouth, Observed indicators:Physica 1 conditions, Blood analysis of liver function, Kidney function, blood coag ulation, AFP and CA19-9, the imaging changes of the tumor.Result1. The two groups before treatment the consistency of good, the difference was not statistically significant (P> 0.05).2. The response rate of the two groups (RR) to assess differences in the t reatment group and the control group, RR was not statistically significan t (P> 0.05), After one month efficient respectively in both groups (treat ment group:10%,15%, control group:10%,5%). Effective rate of 3 months (treatment group:15%, control group:5%). Although the the difference was not statistically significant therapeutic effect,But after a month jianp ihuayu decoction group deterioration (PD) number of cases less than the c ontrol group (3<4), worsening after 3 months jianpihuayu decoction grou p (PD) compared with the control group is small number of cases (10< 12), after 3 months jianpihuayu decoction set of partial remission (PR) The n umber of cases more than the control group (6> 2). The Disease remission rate although the difference was not statistically significant efficacy, Whether after a month or 3 months of treatment, the treatment group were higher than the control group in Disease remission rate.3. Liver function:Two groups of patients after TACE for Jianpi Huayu deco ction traditional Chinese medicine after 1 month AST, ALT, TB, ALB differ ence was statistically significant (P<0.05), two groups of patients aft er TACE for jianpihuayu decoction medicine treatment after 3 monthes AST, ALT, TB, ALB difference was statistically significant (P<0.05).4. Tumor markers:CA19-9 difference between the two groups was no signific ant difference (P>0.05); TACE two groups of patients after one months AF P difference was no statistically significant (P= 0.032<0.05), two grou ps of patients with TACE after three months AFP difference was statistica lly significant (P= 0.034<0.05). Two groups of patients after 1 month a nd 3 months after treatment there was no statistically significant differ ence AFP decline in value(P>0.05).5. QOL quality of life:loss of appetite, mental, sleep, fatigue, pain in the five symptoms Hepatocellular Carcinoma a month after TACE patients we re symptom score difference after the test and statistically significant (P<0.05), except loss of appetite. After 3 months the two groups of pati ents appetite, sleep two symptoms difference was statistically significan t (P<0.05), the spirit of the two groups after 3 months, fatigue, pain, mental, three symptoms was no significant difference (P> 0.05). Five ov erall symptom score, one month after TACE compare the two groups total sc ore (z= 3.136, P= 0.002) difference was statistically significant (P< 0.05),3 months comparison of the total score (z= 3.098, P= 0.02) diffe rence was statistically significant (P<0.05).6.Two living quality KPS Rating:TACE two groups of patients after a mont hs of KPS scores (z= 2.230, P-0.026) difference was statistically sign ificant (P<0.05), after 3 months Comparison (z= 1.990, P= 0.047) diff erence was statistically significant (P<0.05).ConclusionJianpi Huayu prescriptions traditional Chinese medicine in improvi ng patients with hepatocellular carcinoma after TACE spleen deficiency b1 ood stasis syndrome patients have a positive role, to a certain extent, c an improve liver function in patients, improve patients’sleep and diet, to improve the quality of life of patients. |
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