| Objective:By hydrogen breath test (diarrhea type irritable bowel syndrome (IBS) different types of syndrome in TCM and small intestinal bacterial overgrowth (SIBO) and export-blind through the relationship between time (OCTT) and to investigate the correlation of IBS-D TCM syndrome type with Sibo and OCTT, provide a certain basis for the syndrome differentiation and treatment of the disease of TCM syndrome type of objective and clinical.Methods:Collected in February 2015 February 2016 in Fujian Province, the second people’s hospital outpatient, hospital and medical examination center with IBS-D western medicine diagnostic criteria and diagnostic standard of Chinese medicine belongs to the stagnation of the liver qi and deficiency of the spleen, spleen deficiency and dampness resistance, damp heat in spleen and stomach, spleen and kidney Yang four syndrome types of patients 60 cases. Collected from patients with general information and clinical data:name, sex, age, colonoscopy, fecal ob, blood routine, biochemical indexes, using statistical methods IBS-D TCM syndrome type with Sibo and OCTT correlation analysisResults:1.The relationship between SIBO and age:the chi square test, P< 0.05, the differenc e was statistically significant; the comparison between two two groups:20-29 group a nd 40-49 group, P<0.05, the difference was statistically significant, with 30-39,50-5 9 group, P>0.05, there was no significant difference between group 3,0-39 and 40-49, respectively; 50-59 group showed P>0.05, the difference was not statistically significan t; 40-49 group compared with 50-59 group, P< 0.05, the difference was statistically s ignificant. The 40-49 group compared with 20-29 group and 50-59 group, SIBO positi ve patients were more positive, the number of SIBO among the other age groups had no significant difference.2.the relationship between age and P>0.05:OCTT, the difference was not statistically significant.3.Various types of relationship with SIBO:three groups of small intestinal bacterial ov ergrowth by chi square test, P=0.04< 0.05, the difference was statistically significant. The positive rate of SIBO:the positive rate of liver stagnation and spleen deficiency group was 67.9%, the positive rate of spleen dampness group was 50%, the positive rate was 32% in the SSDH group. The comparison between two two groups:liver st agnation and spleen deficiency and spleen group:P=0.01< 0.05, the difference was st atistically significant; liver stagnation and spleen deficiency group and spleen dampness group:P=0.53>0.05, the difference was not statistically significant; spleen group and spleen dampness group:P=0.55>0.05, the difference was not statistically significant. Th e positive rate of SIBO was higher than that of visible liver stagnation and spleen def iciency and damp heat syndrome of spleen, spleen dampness group had no significant difference; no significant difference between the group and the spleen dampness splee n group in the positive rate of SIBO.4.Comparison of various types of syndrome and OCTT:the number of OCTT of the t hree groups, the situation by chi square test,P< 0.05,the difference has statistical signif icance. Summarize and analyze the OCTT ratio in each group, showed that liver stagn ation and spleen deficiency group to OCTT was prolonged, group of damp heat in th e spleen and stomach to the OCTT too fast based, spleen deficiency and dampness re sistance group are mainly normal OCTT.5.Comparison of SIBO and OCTT:counting data using chi square test, P< 0.05, the d ifference was statistically significant. In SIBO positive patients, OCTT was the domina nt, OCTT normal times, OCTT too fast less; SIBO negative patients, OCTT too fast f or more, OCTT normal times, OCTT extended least.Conclusions:1.IBS-D different TCM syndrome types of SIBO and OCTT results are different, the use of hydrogen breath test to assess the situation of SIBO and OCTT, is helpful to TCM syndrome differentiation.2.hydrogen breath test as a noninvasive, simple and reliable detection method, in the use of IBS-D in the study of TCM syndrome type objective has obvious value. |